{"id":"W2105150244","doi":"10.1038/sj.tpj.6500407","title":"Analysis of nucleotide diversity of NAT2 coding region reveals homogeneity across Native American populations and high intra-population diversity","year":2006,"lang":"en","type":"article","venue":"The Pharmacogenomics Journal","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine","funders":"Wellcome Trust","keywords":"Haplotype; Genetic diversity; Biology; Genetics; Population; N-acetyltransferase; Coding region; Nucleotide diversity; Genotype; Gene; Demography; Acetylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004430612,0.0001079681,0.0002495571,0.00009702222,0.0007397904,0.00001639164,0.0001978075,0.00003661621,0.000006131803],"category_scores_gemma":[0.00001526613,0.00009559608,0.0001839744,0.0002836705,0.0001823824,0.000009882279,0.000617095,0.0001107489,9.056838e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006796864,"about_ca_system_score_gemma":0.00001547346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00282501,"about_ca_topic_score_gemma":0.0007591705,"domain_scores_codex":[0.9990917,0.0001317842,0.0002881715,0.0001618442,0.0001674433,0.0001590785],"domain_scores_gemma":[0.9990642,0.00002245835,0.0005372899,0.0001478514,0.0001723364,0.00005586032],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001382586,0.00006367631,0.7155592,0.00000670181,0.0006395711,0.00000280676,0.0003264493,0.007410102,0.2744043,0.0001472706,0.00007616843,0.001225484],"study_design_scores_gemma":[0.0004302236,0.00006873626,0.9622583,0.000004243396,0.0008658455,0.00002052712,0.0002785942,0.001078001,0.03450508,0.0003502962,0.00002188539,0.000118244],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953995,0.0001488664,0.003932008,0.0001021735,0.00006487271,0.0001085897,0.0002209253,0.000002516781,0.0000205938],"genre_scores_gemma":[0.9991351,0.000349145,0.0002681538,0.00005247756,0.00010154,5.650534e-7,0.00006842917,0.000006485892,0.00001812971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2466991,"threshold_uncertainty_score":0.5689945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02529746638284292,"score_gpt":0.3009623649312633,"score_spread":0.2756648985484204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}