{"id":"W2105197802","doi":"10.1080/15548627.2015.1108507","title":"<i>MIR517C</i>inhibits autophagy and the epithelial-to-mesenchymal (-like) transition phenotype in human glioblastoma through KPNA2-dependent disruption of TP53 nuclear translocation","year":2015,"lang":"en","type":"article","venue":"Autophagy","topic":"MicroRNA in disease regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":101,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Biology; Epithelial–mesenchymal transition; Autophagy; Vimentin; Gene knockdown; Cancer research; ATG5; microRNA; SNAI1; Cell culture; Cell biology; Downregulation and upregulation; Apoptosis; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000154633,0.0003870521,0.0004566878,0.0002185248,0.0002176795,0.0003085916,0.0002216675,0.0003239318,0.001197967],"category_scores_gemma":[0.0001812094,0.0001587268,0.0003319713,0.0001546569,0.0002334437,0.0001518938,0.0001425377,0.000523073,0.0005184317],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002550981,"about_ca_system_score_gemma":0.0002420583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008617013,"about_ca_topic_score_gemma":0.000929315,"domain_scores_codex":[0.9998692,0.0000296116,0.00002441174,0.00001750525,0.00002504801,0.00003413804],"domain_scores_gemma":[0.9999427,0.000009498686,0.00001495452,0.00001004656,0.000009573578,0.00001333297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002117193,0.0003818759,0.0004494957,0.0001302384,0.00007394045,0.0001367896,0.00002835223,0.0003399909,0.9877405,0.0003085728,0.000967102,0.007325948],"study_design_scores_gemma":[0.0002471053,0.00225304,0.004444594,0.00001082837,0.00008563985,0.0003818592,0.00003107005,0.002382087,0.9854251,0.00007485486,0.00465084,0.00001299799],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9919751,0.002246151,0.001082178,0.0002765144,0.0001276167,0.00008524951,0.0004923459,0.0003767255,0.00333798],"genre_scores_gemma":[0.9956404,0.0008139228,0.001124338,0.0001928252,0.00002740422,0.00008024064,0.0007785583,0.00003708229,0.001305056],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197967,"threshold_uncertainty_score":0.004007578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01001343255158227,"score_gpt":0.2511110141044059,"score_spread":0.2410975815528236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}