{"id":"W2105238928","doi":"10.2174/138920210790217990","title":"Investigation of Molecular Mechanism of Chronic Pain in the Anterior Cingulate Cortex Using Genetically Engineered Mice","year":2009,"lang":"en","type":"article","venue":"Current Genomics","topic":"Pain Mechanisms and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Mechanism (biology); Chronic pain; Genetically modified mouse; Knockout mouse; Anterior cingulate cortex; Neuroscience; Transgene; Genetically engineered; Medicine; Gene; Biology; Bioinformatics; Genetics; Cognition","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004830606,0.0008883139,0.0005954712,0.0008316083,0.0003663551,0.000641215,0.0008627019,0.0008401221,0.001941682],"category_scores_gemma":[0.0002579272,0.0003543271,0.0004626609,0.0003808239,0.00102744,0.0006627906,0.0003907815,0.00187022,0.0005591188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005078386,"about_ca_system_score_gemma":0.000648507,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007843549,"about_ca_topic_score_gemma":0.001131251,"domain_scores_codex":[0.9997091,0.00005246636,0.00003223481,0.00007568634,0.00008217453,0.00004829115],"domain_scores_gemma":[0.9998075,0.00004441711,0.00007198623,0.00002068785,0.00002322899,0.00003212498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002118239,0.0001091672,0.0002022433,0.0002428737,0.00002403262,0.0002179258,0.00004085826,0.0001445344,0.9866439,0.00370781,0.0003181849,0.008136754],"study_design_scores_gemma":[0.0004739266,0.002463228,0.007742127,0.0003743757,0.0003772369,0.002924446,0.0001668082,0.002927461,0.9340468,0.003176189,0.04526321,0.00006421904],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7171613,0.06099965,0.1905172,0.007476588,0.001266279,0.001020083,0.003111879,0.001973299,0.0164737],"genre_scores_gemma":[0.7484843,0.09987537,0.131374,0.001390845,0.0003091326,0.001471888,0.002127558,0.0002801626,0.01468684],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001941682,"threshold_uncertainty_score":0.006495595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02282026118786955,"score_gpt":0.2675999593554887,"score_spread":0.2447796981676192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}