{"id":"W2105268691","doi":"10.2337/diabetes.53.11.2893","title":"Hepatic Lipase mRNA, Protein, and Plasma Enzyme Activity Is Increased in the Insulin-Resistant, Fructose-Fed Syrian Golden Hamster and Is Partially Normalized by the Insulin Sensitizer Rosiglitazone","year":2004,"lang":"en","type":"article","venue":"Diabetes","topic":"Diet, Metabolism, and Disease","field":"Medicine","cited_by":71,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Heart and Stroke Foundation of Canada","keywords":"Internal medicine; Endocrinology; Rosiglitazone; Insulin; Hyperinsulinemia; Hamster; Mesocricetus; Chemistry; Hepatic lipase; Hepatocyte; Insulin resistance; Lipoprotein lipase; Biology; Medicine; Adipose tissue; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006991863,0.0003839643,0.0006175405,0.000105896,0.0002064276,0.0001828715,0.0001657641,0.0001594012,0.00005561499],"category_scores_gemma":[0.0004949064,0.000236056,0.0001154794,0.0003088065,0.0003320849,0.0002639478,0.00009458239,0.0003342764,0.00002129339],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000417611,"about_ca_system_score_gemma":0.0001622098,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001062622,"about_ca_topic_score_gemma":0.0002016998,"domain_scores_codex":[0.9976873,0.0003743678,0.000417975,0.0004948799,0.0004746637,0.0005508603],"domain_scores_gemma":[0.9985206,0.0002898571,0.0001618346,0.0005949996,0.00009708145,0.0003355859],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007526624,0.003227607,0.09597745,0.001480558,0.0007061365,0.0003860469,0.02358649,0.000004274475,0.846693,0.0003902606,0.004847323,0.01517422],"study_design_scores_gemma":[0.03172043,0.0009342408,0.4566912,0.0008196845,0.001089277,0.00002051865,0.001684156,0.001069596,0.4977676,0.001504084,0.005663135,0.001036073],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9885743,0.004298314,0.000003834172,0.004965303,0.00005748361,0.001527016,0.000292174,0.00005596842,0.0002255694],"genre_scores_gemma":[0.9924471,0.0001813026,0.00009713109,0.006717989,0.0001613989,0.0001924015,0.00004178035,0.00004257189,0.0001183626],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3607138,"threshold_uncertainty_score":0.9626085,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009621298776392633,"score_gpt":0.2286755140714013,"score_spread":0.2190542152950086,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}