{"id":"W2105331656","doi":"10.1002/open.201300040","title":"<i>N</i>‐Aryl Isoleucine Derivatives as Angiotensin II AT<sub>2</sub> Receptor Ligands","year":2014,"lang":"en","type":"article","venue":"ChemistryOpen","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Vetenskapsrådet; Alzheimer Society; Canadian Diabetes Association","keywords":"Aryl; Isoleucine; Chemistry; Angiotensin II; Combinatorial chemistry; Stereochemistry; Receptor; Organic chemistry; Amino acid; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008931816,0.0003529494,0.0002249792,0.00008395472,0.00008005036,0.0001978932,0.0002394059,0.0001616024,0.0009378497],"category_scores_gemma":[0.00009995681,0.00009655831,0.0001074241,0.0001279729,0.000123016,0.0001525333,0.0001411824,0.000289186,0.0005323463],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000181107,"about_ca_system_score_gemma":0.00009817071,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000300165,"about_ca_topic_score_gemma":0.000952356,"domain_scores_codex":[0.9999291,0.00002548949,0.000005437377,0.000009991601,0.0000149377,0.00001503364],"domain_scores_gemma":[0.9999471,0.000008476438,0.00001646136,0.000004458351,0.000008336233,0.00001520447],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001522219,0.0000184026,0.0001106524,0.00006175828,0.000005719467,0.0001184919,0.00001202637,0.0002417063,0.9945734,0.0002065847,0.00009061972,0.004408468],"study_design_scores_gemma":[0.00002566021,0.0004167901,0.0009206114,0.000006335475,0.00001839258,0.0003689223,0.00001377724,0.0005095693,0.9894807,0.00004690514,0.00818503,0.000007222392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9656557,0.009237093,0.01225774,0.0001907039,0.00009040015,0.00006230508,0.0003784026,0.0002069073,0.01192071],"genre_scores_gemma":[0.9823279,0.00445859,0.009208717,0.0001293746,0.00003053826,0.00002844226,0.0003328359,0.00004227333,0.003441324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009378497,"threshold_uncertainty_score":0.00313741,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005915679718221901,"score_gpt":0.2122644050185239,"score_spread":0.206348725300302,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}