{"id":"W2105332411","doi":"10.1042/bst0360901","title":"Glucolipotoxicity of the pancreatic β-cell: myth or reality?","year":2008,"lang":"en","type":"review","venue":"Biochemical Society Transactions","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":69,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Canadian Institutes of Health Research","keywords":"Insulin; Beta cell; Endocrinology; Internal medicine; Diabetes mellitus; Pancreatic islets; Type 2 diabetes; Insulin oscillation; In vivo; Secretion; Biology; In vitro; Islet; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008330235,0.0007930211,0.001609596,0.001114402,0.0003116645,0.001296685,0.001039888,0.001577049,0.001755201],"category_scores_gemma":[0.000799927,0.0002194812,0.0002592524,0.001570169,0.002072813,0.004317188,0.0007784538,0.002394743,0.001518425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000627933,"about_ca_system_score_gemma":0.0008022758,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007211459,"about_ca_topic_score_gemma":0.001235357,"domain_scores_codex":[0.9998584,0.0000311142,0.00002250225,0.00002687455,0.00004520376,0.00001596626],"domain_scores_gemma":[0.9996264,0.0001778822,0.0000482398,0.00001997568,0.00007832266,0.00004922395],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001432124,0.00004561842,0.0003856776,0.009239295,0.00005741576,0.0007402415,0.0001647401,0.0002416164,0.001931955,0.0124334,0.06654992,0.9080669],"study_design_scores_gemma":[0.00003045036,0.0001146995,0.001117709,0.003323381,0.0000527058,0.00392347,0.0003448181,0.00009664403,0.0003926455,0.01279355,0.9777777,0.0000322829],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000977461,0.9972096,0.00009857965,0.001759121,0.0004043248,0.000001042637,0.000004543213,0.000005716411,0.0004193294],"genre_scores_gemma":[0.0008106953,0.9971691,0.0001258704,0.0007844527,0.000700558,0.000002602016,0.000006617976,0.000001181394,0.0003989185],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001755201,"threshold_uncertainty_score":0.005871773,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05433945963330037,"score_gpt":0.3138945120244981,"score_spread":0.2595550523911977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}