{"id":"W2105354953","doi":"10.1158/1541-7786.mcr-08-0469","title":"Cadherin-Cadherin Engagement Promotes Cell Survival via Rac1/Cdc42 and Signal Transducer and Activator of Transcription-3","year":2009,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Cytokine Signaling Pathways and Interactions","field":"Medicine","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"STAT3; Cadherin; RAC1; STAT protein; CDC42; Cell biology; Biology; Cancer research; Signal transduction; Activator (genetics); Cell; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008480522,0.0002083303,0.0001055054,0.0002237643,0.0001727049,0.0003124385,0.00007671072,0.0001276837,0.001727808],"category_scores_gemma":[0.00006761913,0.0001071568,0.0001523975,0.0001175149,0.000157664,0.0001547833,0.0001984957,0.0002926139,0.000449345],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001590641,"about_ca_system_score_gemma":0.0001925562,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004771829,"about_ca_topic_score_gemma":0.001305087,"domain_scores_codex":[0.9998741,0.00002100251,0.000004850118,0.00001058832,0.00003214137,0.00005718301],"domain_scores_gemma":[0.9999566,0.000005971123,0.00000922773,0.000003527935,0.000007490902,0.00001717092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001444816,0.00003655674,0.0004547436,0.00003087486,0.000003601702,0.00008252168,0.00001470516,0.0000419461,0.995829,0.0002850463,0.0001595917,0.002916958],"study_design_scores_gemma":[0.00004511932,0.00033383,0.02059769,0.00001037589,0.00001679956,0.0005443693,0.0000911597,0.002785407,0.9679316,0.0002082565,0.007430208,0.000005161687],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920318,0.002083923,0.001406869,0.0001729301,0.00001898589,0.00001380768,0.0001234747,0.00005973523,0.004088396],"genre_scores_gemma":[0.9965964,0.0008179148,0.0005893841,0.00003447276,0.000009472056,0.000009135557,0.0001777733,0.000003835281,0.001761655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001727808,"threshold_uncertainty_score":0.00578016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07280287764102782,"score_gpt":0.3790293880781854,"score_spread":0.3062265104371575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}