{"id":"W2105365840","doi":"10.1046/j.1432-1327.2001.02415.x","title":"All or none fibrillogenesis of a prion peptide","year":2001,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Fibrillogenesis; Fibril; Peptide; Chemistry; Amyloid fibril; Amyloid (mycology); Biophysics; Peptide sequence; Biochemistry; Protein structure; Amyloid disease; Protein folding; Amyloid β; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003044069,0.0002886912,0.0001850448,0.000201917,0.0002072788,0.0003286939,0.0001731047,0.0001282058,0.0005053633],"category_scores_gemma":[0.0003697449,0.0001436677,0.0002204905,0.00007768635,0.0001946323,0.0003342314,0.0001697453,0.0002976081,0.0002627902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001311996,"about_ca_system_score_gemma":0.0001504322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003359261,"about_ca_topic_score_gemma":0.0004971952,"domain_scores_codex":[0.9998786,0.00002503124,0.000009700045,0.0000309872,0.00003170692,0.00002399923],"domain_scores_gemma":[0.9996771,0.00008667801,0.00005947319,0.00006775412,0.00005326482,0.00005573939],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009240807,0.00002367886,0.001519684,0.00004670288,0.00001143174,0.0002356567,0.00005216313,0.0001973616,0.9937226,0.001069603,0.00005031845,0.002978304],"study_design_scores_gemma":[0.000007117996,0.0001838367,0.006226099,0.000008005114,0.00002786247,0.0009389995,0.00004267353,0.002630921,0.9877108,0.0007755051,0.001439205,0.000008943118],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908467,0.001038907,0.006265222,0.00002320662,0.00001499301,0.000009231701,0.00007685198,0.00004628003,0.001678534],"genre_scores_gemma":[0.9962294,0.0004160431,0.002121502,0.00002007959,0.000004396567,0.000003836776,0.00009849683,0.00001768442,0.001088596],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005053633,"threshold_uncertainty_score":0.001690567,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0162779805168537,"score_gpt":0.2535015644340857,"score_spread":0.237223583917232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}