{"id":"W2105365840","doi":"10.1046/j.1432-1327.2001.02415.x","title":"All or none fibrillogenesis of a prion peptide","year":2001,"lang":"en","type":"article","venue":"European Journal of Biochemistry","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Occupational Cancer Research Centre; University of Toronto","funders":"","keywords":"Fibrillogenesis; Fibril; Peptide; Chemistry; Amyloid fibril; Amyloid (mycology); Biophysics; Peptide sequence; Biochemistry; Protein structure; Amyloid disease; Protein folding; Amyloid β; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004299024,0.0001356557,0.0001756328,0.00003488574,0.00003017842,0.00001479448,0.0003065182,0.00004746118,0.0001093651],"category_scores_gemma":[0.0002158101,0.0001107775,0.0002104743,0.00008211612,0.00005832732,0.000004461368,0.0001096169,0.00008113297,0.000005898516],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000113523,"about_ca_system_score_gemma":0.0001004214,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001145314,"about_ca_topic_score_gemma":2.734683e-7,"domain_scores_codex":[0.9989543,0.00009753356,0.0004454849,0.0001622759,0.0001715995,0.000168834],"domain_scores_gemma":[0.9989752,0.0000109046,0.0004290259,0.0002679486,0.0001590503,0.00015793],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006531873,0.00005878937,0.001162519,0.00004524144,0.0001005131,0.0001598186,0.00001718777,0.00002786103,0.9764914,5.275474e-7,0.002950984,0.018332],"study_design_scores_gemma":[0.0007810579,0.0003878892,0.001634873,0.0001122424,0.00005070339,0.0006623409,0.00006524167,0.000004987677,0.9175302,0.000004079215,0.07860941,0.0001569352],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906909,0.006845917,0.0007657644,0.0001414739,0.00006829378,0.00004266462,0.00001061381,0.000004130356,0.001430245],"genre_scores_gemma":[0.9922385,0.004792947,0.001609381,0.0001603582,0.0005439807,4.041448e-7,0.00001503059,0.00002712775,0.0006123086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07565843,"threshold_uncertainty_score":0.4517374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0162779805168537,"score_gpt":0.2535015644340857,"score_spread":0.237223583917232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}