{"id":"W2105391259","doi":"10.1093/brain/awh249","title":"Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies","year":2004,"lang":"en","type":"article","venue":"Brain","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":308,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; University of Toronto; Bundesministerium für Gesundheit; Health Canada; Bundesamt für Gesundheit; European Commission","keywords":"Fatal familial insomnia; Disease; Proportional hazards model; Survival analysis; Medicine; Creutzfeldt-Jakob Syndrome; Internal medicine; Kuru; Virology; Oncology; Prion protein; Scrapie","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002017668,0.0001079556,0.0001233812,0.00005615669,0.00003955181,0.00001084879,0.0001085483,0.00006574352,0.00003485891],"category_scores_gemma":[0.00004264253,0.0001036681,0.00005904111,0.00007891077,0.00009845476,0.00000510629,0.00003388387,0.00004666822,8.162559e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00000835088,"about_ca_system_score_gemma":0.00007811511,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001004364,"about_ca_topic_score_gemma":0.00008467731,"domain_scores_codex":[0.9993166,0.00003332154,0.0001731381,0.0002157173,0.00009960321,0.0001616214],"domain_scores_gemma":[0.9996293,0.000007752144,0.0000462336,0.0001733672,0.00001318989,0.0001301732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005703239,0.0003046501,0.3538212,0.0003029341,0.00008900141,0.00005253684,0.0006346621,0.0003184361,0.6314664,0.004681896,0.0001435202,0.007614467],"study_design_scores_gemma":[0.006634311,0.0008661735,0.7841472,0.0005147583,0.0001015133,0.00001489052,0.000573293,0.00003585054,0.1521831,0.008690415,0.04525767,0.0009808653],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932831,0.005786125,0.0001732832,0.0001913011,0.00003847722,0.000125891,0.00005503846,0.00000857458,0.0003382344],"genre_scores_gemma":[0.9992474,0.0002400478,0.0001057855,0.0001230489,0.00008490242,0.0000119229,0.00002772131,0.00001502501,0.0001441958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4792833,"threshold_uncertainty_score":0.4227461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01052237456126461,"score_gpt":0.2522978024152918,"score_spread":0.2417754278540271,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}