{"id":"W2105408675","doi":"10.1152/ajpheart.00388.2003","title":"Inhibition of L-type Ca<sup>2+</sup>current by C-type natriuretic peptide in bullfrog atrial myocytes: an NPR-C-mediated effect","year":2003,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"","keywords":"Bullfrog; Adenylyl cyclase; Internal medicine; Endocrinology; Chemistry; Receptor; Natriuretic peptide; Agonist; Inward-rectifier potassium ion channel; Atrial natriuretic peptide; Secretagogue; Biology; Ion channel; Medicine; Heart failure","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002646556,0.0002952373,0.0004641044,0.00009992193,0.0001513949,0.0003036993,0.0004595339,0.0005079081,0.00124276],"category_scores_gemma":[0.0002063148,0.0001349983,0.0002689378,0.00008265702,0.0004584311,0.0003524692,0.0002192661,0.0006887525,0.0003754749],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004293781,"about_ca_system_score_gemma":0.0003501065,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003327722,"about_ca_topic_score_gemma":0.004510437,"domain_scores_codex":[0.9998807,0.00001334972,0.00001436803,0.00002343838,0.00003165773,0.00003645604],"domain_scores_gemma":[0.9998546,0.00004359796,0.0000263341,0.00001426605,0.00002342713,0.00003768453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006883253,0.000007277853,0.00006561528,0.00004520942,0.000004531929,0.00004405576,0.00001627665,0.000009075524,0.9992751,0.00002646987,0.0000250443,0.0004124141],"study_design_scores_gemma":[0.0002069845,0.001341574,0.03576174,0.00002416231,0.00007571347,0.000505327,0.00009308451,0.001479376,0.9551815,0.00006691684,0.005249596,0.0000139903],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896476,0.005773121,0.001360947,0.0002842723,0.00006521934,0.00005852522,0.0002939808,0.00006852283,0.002447794],"genre_scores_gemma":[0.992714,0.001968661,0.002349833,0.0002684528,0.00005587707,0.00008067766,0.0004079773,0.00002793413,0.00212654],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003327722,"threshold_uncertainty_score":0.006616712,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007128586203321898,"score_gpt":0.2529144648816736,"score_spread":0.2457858786783517,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}