{"id":"W2105435914","doi":"10.1186/gm28","title":"Gene-gene and gene-environment interactions: new insights into the prevention, detection and management of coronary artery disease","year":2009,"lang":"en","type":"article","venue":"Genome Medicine","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Ontario Genomics Institute; Genome Canada; Heart and Stroke Foundation of Canada; Ontario Genomics; Pfizer","keywords":"Genome-wide association study; Gene; Computational biology; Genetic association; Genetics; Human genetics; Biology; Bioinformatics; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004607365,0.0009199634,0.00216268,0.0016493,0.0005152667,0.002671208,0.001153943,0.00229404,0.0041908],"category_scores_gemma":[0.006127414,0.0004361697,0.0007567411,0.001303536,0.002596965,0.003844979,0.001287108,0.002895078,0.0007143227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008216035,"about_ca_system_score_gemma":0.002106749,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001491076,"about_ca_topic_score_gemma":0.002912988,"domain_scores_codex":[0.9979901,0.001255065,0.00009649061,0.0002130097,0.0003521864,0.00009311395],"domain_scores_gemma":[0.9963309,0.002640501,0.0004026164,0.0001991253,0.0002241471,0.0002026741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0009820468,0.0006415807,0.0892642,0.00351236,0.001381445,0.001397291,0.0005683778,0.004278676,0.007115111,0.07161881,0.02960538,0.7896348],"study_design_scores_gemma":[0.0002764259,0.001395928,0.2047684,0.002059022,0.001677737,0.007316272,0.001604134,0.01009979,0.002372013,0.4905519,0.2775376,0.0003407846],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.04155366,0.6688992,0.07411231,0.1984498,0.003205918,0.00006629251,0.0006499873,0.0002880112,0.0127748],"genre_scores_gemma":[0.2684063,0.6276444,0.05701465,0.02724466,0.01389541,0.0001379861,0.0002982089,0.00006870203,0.005289642],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004607365,"threshold_uncertainty_score":0.02436638,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033244264628357,"score_gpt":0.2449625814844681,"score_spread":0.2346301388381845,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}