{"id":"W2105487299","doi":"10.1002/cbf.3121","title":"Inhibition of MCL‐1 by obatoclax sensitizes Sp2/0‐Ag14 hybridoma cells to glutamine deprivation‐induced apoptosis","year":2015,"lang":"en","type":"article","venue":"Cell Biochemistry and Function","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Laurentian University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Apoptosis; Glutamine; Chemistry; Downregulation and upregulation; Cancer research; Pharmacology; Molecular biology; Biology; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000158959,0.0001950048,0.0001886572,0.00003708261,0.00006213634,0.00002199967,0.00006035235,0.0002121159,0.00001166216],"category_scores_gemma":[0.00005662197,0.0002096805,0.00006885511,0.0001327877,0.00005512428,0.000009009436,0.0000759371,0.00007899229,0.000009142707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000246355,"about_ca_system_score_gemma":0.00007786651,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003433494,"about_ca_topic_score_gemma":0.000002202308,"domain_scores_codex":[0.9989328,0.0000274564,0.0002503208,0.0004255697,0.0001604782,0.0002033792],"domain_scores_gemma":[0.9991677,0.000008634439,0.0001179843,0.0002956563,0.0001903983,0.0002196695],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002553957,0.00006390888,0.00006066351,0.00006211668,0.00002051328,1.629673e-7,0.00003565599,0.00001702766,0.96951,0.000002374748,0.0275936,0.00237858],"study_design_scores_gemma":[0.0009694864,0.0002332277,0.0000663992,0.00001643105,0.00005155426,0.000007050864,0.0001946022,0.00001615335,0.9610137,0.00002428527,0.03717867,0.0002284568],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947985,0.001089451,0.001918209,0.00007296602,0.0006762485,0.000173578,0.00007547949,0.00001909314,0.001176412],"genre_scores_gemma":[0.9965055,0.0002074008,0.0002662507,0.0002524387,0.0009599003,0.00002063229,0.0005257731,0.00002057733,0.001241521],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009585068,"threshold_uncertainty_score":0.8550523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009078947064200612,"score_gpt":0.2040792319746835,"score_spread":0.1950002849104829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}