{"id":"W2105497795","doi":"10.1016/j.cjca.2011.02.005","title":"Targeted Gene Therapy for the Treatment of Heart Failure","year":2011,"lang":"en","type":"review","venue":"Canadian Journal of Cardiology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute","keywords":"Medicine; Heart failure; Genetic enhancement; Intensive care medicine; Clinical trial; Gene delivery; Gene transfer; Bioinformatics; Gene; Internal medicine; Genetics; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006619699,0.00090099,0.001571707,0.001725089,0.000343035,0.0008969423,0.0009451286,0.001259644,0.002595829],"category_scores_gemma":[0.0005542078,0.0002503915,0.0004276738,0.001459856,0.0007928885,0.0007898814,0.0005163887,0.00250303,0.001652844],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009213511,"about_ca_system_score_gemma":0.001092346,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002544753,"about_ca_topic_score_gemma":0.005687967,"domain_scores_codex":[0.9998544,0.00002422543,0.00001344788,0.00002413733,0.00006492037,0.00001874971],"domain_scores_gemma":[0.9997566,0.0001270224,0.00002629947,0.000007198184,0.00005754603,0.00002524094],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001406298,0.0001567017,0.0001096176,0.006327946,0.00008759885,0.0003099648,0.00004841286,0.0004959853,0.005803179,0.006783283,0.03763172,0.9421049],"study_design_scores_gemma":[0.00008926649,0.0001481919,0.0006003305,0.001483162,0.0001110271,0.001449319,0.00003964555,0.0002148592,0.001502971,0.002720936,0.9916113,0.00002896926],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001180276,0.9980965,0.0003207975,0.0002738753,0.0002922421,0.000004968917,0.00001016734,0.000007792632,0.000875643],"genre_scores_gemma":[0.001075137,0.9973661,0.0003722625,0.0001904969,0.0002024316,0.000008406176,0.00002025418,0.000002125092,0.0007626943],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002595829,"threshold_uncertainty_score":0.00868398,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05376698660445096,"score_gpt":0.3274527717617721,"score_spread":0.2736857851573212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}