{"id":"W2105517676","doi":"10.1128/mcb.21.17.5992-6005.2001","title":"Histone Deacetylase 4 Possesses Intrinsic Nuclear Import and Export Signals","year":2001,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":197,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Nuclear export signal; HDAC4; Nuclear localization sequence; Nuclear transport; Biology; Cell biology; Cytoplasm; Nuclear protein; Cell nucleus; Mef2; Histone; Histone deacetylase; Biochemistry; Transcription factor; Enhancer; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000148992,0.0003716621,0.0003557719,0.0001592561,0.0002627777,0.0003577699,0.000273251,0.0002371276,0.001325891],"category_scores_gemma":[0.0001634353,0.0001900855,0.0004032545,0.0001711213,0.0002139039,0.0002488918,0.0003287792,0.0003607152,0.0007299202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004613923,"about_ca_system_score_gemma":0.0004087423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006871684,"about_ca_topic_score_gemma":0.001085167,"domain_scores_codex":[0.999842,0.00002200995,0.0000171198,0.00004178938,0.00004196334,0.00003502379],"domain_scores_gemma":[0.999884,0.00001231366,0.00003343998,0.00002153305,0.00002154874,0.00002710468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007602242,0.00001320472,0.001253007,0.00005385982,0.00001300144,0.00008706385,0.000007684189,0.00008496158,0.9960507,0.00025159,0.0000455726,0.002063513],"study_design_scores_gemma":[0.00002025492,0.0001377474,0.01072568,0.000004314584,0.00003174257,0.0007545851,0.00001447437,0.0009566554,0.9810728,0.0001118999,0.006161973,0.000007939002],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986578,0.002044713,0.008580402,0.0001286019,0.0000425907,0.0000161914,0.0005333567,0.000125046,0.001951126],"genre_scores_gemma":[0.985666,0.001022204,0.00643138,0.00005219652,0.00002785607,0.00002494208,0.002483684,0.00002264501,0.004269053],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001325891,"threshold_uncertainty_score":0.004435599,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007232454669176213,"score_gpt":0.254485997182393,"score_spread":0.2472535425132168,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}