{"id":"W2105567212","doi":"10.1186/bcr3231","title":"Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer","year":2012,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Surgical oncology; Medicine; Breast cancer; Oncology; Cisplatin; Internal medicine; Chemotherapy; Metastatic breast cancer; Cancer; Randomized controlled trial; Open label","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.002566039,0.0002680739,0.001448701,0.0004747404,0.00009133147,0.0000166862,0.0003143308,0.00008833096,0.001165345],"category_scores_gemma":[0.00007336721,0.0001840814,0.00009710767,0.001131971,0.0005951209,0.0002731914,0.000169341,0.0004055378,0.000004165093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005316212,"about_ca_system_score_gemma":0.001127886,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01860972,"about_ca_topic_score_gemma":0.0006215135,"domain_scores_codex":[0.9961859,0.0006645887,0.000850139,0.0004339252,0.001145388,0.000720079],"domain_scores_gemma":[0.9972554,0.0006209273,0.0004066515,0.0003988504,0.001029136,0.0002890055],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9292838,0.01864195,0.01022224,0.0001222936,0.001058635,0.000008149474,0.002260865,0.000004132104,0.001998302,0.00002092061,0.00193173,0.03444697],"study_design_scores_gemma":[0.9270204,0.004844456,0.06357855,0.0005267568,0.0003312286,0.00001248797,0.0000800334,0.00007615124,0.003204945,0.00001545639,0.000150245,0.0001592683],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986492,0.0004279234,0.000004871361,0.002923369,0.0001732767,0.006198028,0.002707005,0.000006958608,0.001066573],"genre_scores_gemma":[0.9966008,0.0003527982,0.0001488363,0.0001267589,0.0002734064,0.001474299,0.0001225687,0.00004763428,0.0008529134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05335632,"threshold_uncertainty_score":0.9997478,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07042442315505405,"score_gpt":0.4650166770510589,"score_spread":0.3945922538960048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}