{"id":"W2105567212","doi":"10.1186/bcr3231","title":"Results of a phase II open-label, non-randomized trial of cisplatin chemotherapy in patients with BRCA1-positive metastatic breast cancer","year":2012,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":213,"is_retracted":false,"has_abstract":true,"ca_institutions":"Women's College Hospital; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Surgical oncology; Medicine; Breast cancer; Oncology; Cisplatin; Internal medicine; Chemotherapy; Metastatic breast cancer; Cancer; Randomized controlled trial; Open label","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003986679,0.001317761,0.002510497,0.0003528019,0.0004634915,0.0009529141,0.000792413,0.001239829,0.004946047],"category_scores_gemma":[0.003968811,0.0006497991,0.001281769,0.0003807905,0.0009939844,0.001043105,0.0003762188,0.002328337,0.0006882964],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007599475,"about_ca_system_score_gemma":0.001316369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004445098,"about_ca_topic_score_gemma":0.001250841,"domain_scores_codex":[0.9979807,0.001519235,0.0001035576,0.0001688145,0.0001219566,0.0001059212],"domain_scores_gemma":[0.9971889,0.001157987,0.0006184961,0.0002216161,0.0001710089,0.000642013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.940291,0.0230744,0.003228316,0.0005518362,0.001402024,0.00006327695,0.0000874387,0.0006918116,0.00398572,0.00007256995,0.001071182,0.02548042],"study_design_scores_gemma":[0.8662539,0.1285652,0.003299979,0.00002394732,0.0003987871,0.0000510925,0.00001291176,0.0003428434,0.0004289222,0.00006594486,0.0005465335,0.000009979465],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899662,0.003409107,0.0005906553,0.0005842975,0.0002138787,0.003273774,0.0007593833,0.0000475357,0.001155279],"genre_scores_gemma":[0.9890526,0.002113488,0.001681541,0.0009349958,0.0002915771,0.003302323,0.001431022,0.00002287043,0.001169575],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004946047,"threshold_uncertainty_score":0.02108389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07042442315505405,"score_gpt":0.4650166770510589,"score_spread":0.3945922538960048,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}