{"id":"W2105693845","doi":"10.1212/wnl.0b013e31824e8f1d","title":"No consistent evidence for association between mtDNA variants and Alzheimer disease","year":2012,"lang":"en","type":"review","venue":"Neurology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"Parkinson's UK; National Institute for Health and Care Research; Wellcome Trust","keywords":"Mitochondrial DNA; Disease; Genetic association; Etiology; Biology; Genetics; Alzheimer's disease; Case-control study; Genetic variation; Medicine; Genotype; Single-nucleotide polymorphism; Pathology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003171864,0.0002752683,0.0006784023,0.00005437713,0.00008651896,0.00001566193,0.0001448768,0.0007344149,0.00005053002],"category_scores_gemma":[0.0007603311,0.0002478024,0.0002589164,0.00004116335,0.00005396618,0.000003966978,0.0001243423,0.0002101358,0.00009907381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009897342,"about_ca_system_score_gemma":0.0001455947,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004585663,"about_ca_topic_score_gemma":0.000004748993,"domain_scores_codex":[0.9981835,0.0004675318,0.0003556303,0.0005698709,0.0000798222,0.0003435841],"domain_scores_gemma":[0.9986307,0.0003931787,0.0003385327,0.0003468857,0.00009871335,0.0001919688],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001588249,0.0001965973,0.01266245,0.006708471,0.002578887,0.00003285602,0.00002383489,6.304482e-7,0.0007049459,0.0004546295,0.02971996,0.9453285],"study_design_scores_gemma":[0.0002226266,0.0004726406,0.0005271825,0.00009034964,0.002561549,0.00002251001,8.342234e-8,8.028185e-7,0.000003600079,0.00001396174,0.9958815,0.0002032194],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008086631,0.9962815,0.0002757451,0.0001520345,0.00197625,0.0008269426,0.0002065676,0.00001339835,0.0001866864],"genre_scores_gemma":[0.00008489265,0.9946482,0.0001494885,0.0008956143,0.002499562,0.0002285751,0.0006196855,0.0000447275,0.000829301],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9661615,"threshold_uncertainty_score":0.9999974,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1205491904423623,"score_gpt":0.349827514300592,"score_spread":0.2292783238582297,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}