{"id":"W2105706019","doi":"10.1006/mgme.2000.3000","title":"Biochemical and Molecular Investigations of Patients with Nonketotic Hyperglycinemia","year":2000,"lang":"en","type":"article","venue":"Molecular Genetics and Metabolism","topic":"Metabolism and Genetic Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":53,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Sick Kids Foundation","keywords":"Hyperglycinemia; Glycine; Glycine cleavage system; Gene; Enzyme; Chemistry; Medicine; Biochemistry; Genetics; Biology; Amino acid","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003396889,0.0009523429,0.0006232947,0.002136882,0.0009323099,0.0007096603,0.0004659578,0.0009086329,0.001946562],"category_scores_gemma":[0.002852027,0.0003873877,0.0002988871,0.00100165,0.0006211367,0.0004800864,0.0003537154,0.000642838,0.0003444919],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003368263,"about_ca_system_score_gemma":0.0003232213,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001406932,"about_ca_topic_score_gemma":0.0008146647,"domain_scores_codex":[0.99964,0.00007019566,0.0000728016,0.00006529965,0.0000716775,0.0000800271],"domain_scores_gemma":[0.9989706,0.000404557,0.0001521076,0.00005969792,0.0001059392,0.0003070623],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.003402425,0.0004635115,0.8167391,0.0001389856,0.00009254273,0.1323827,0.001426238,0.0003003386,0.03623259,0.0003747216,0.0003805155,0.008066284],"study_design_scores_gemma":[0.0001129889,0.001210548,0.7586704,0.00002593445,0.0001351839,0.2279463,0.001418485,0.0006489137,0.008138006,0.0005924883,0.001062963,0.00003771199],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997357,0.0004440552,0.0001731044,0.0001099552,0.00001353196,0.00001301778,0.0001428389,0.0000149641,0.001731519],"genre_scores_gemma":[0.9993248,0.000162615,0.0001162301,0.00007050734,0.00002132776,0.00000744957,0.0001222086,0.000004818122,0.0001699607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002136882,"threshold_uncertainty_score":0.006511927,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002793436852707292,"score_gpt":0.1871824870604433,"score_spread":0.184389050207736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}