{"id":"W2105755414","doi":"10.1038/ni.1778","title":"Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori","year":2009,"lang":"en","type":"article","venue":"Nature Immunology","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":438,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"U.S. Public Health Service; National Institutes of Health","keywords":"DC-SIGN; Biology; Acquired immune system; Mycobacterium tuberculosis; Microbiology; Mannose; Pattern recognition receptor; Innate immune system; Cell biology; Virology; Immunology; Dendritic cell; Immune system; Tuberculosis; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002684793,0.0003011183,0.0002656988,0.0003378195,0.0003065507,0.0007790041,0.000172913,0.0004477629,0.001786692],"category_scores_gemma":[0.0003827414,0.0002218754,0.0002411967,0.0001717898,0.0003183839,0.0006008751,0.0006348562,0.0009966703,0.0007252034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004829706,"about_ca_system_score_gemma":0.0003521595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003368182,"about_ca_topic_score_gemma":0.0007366504,"domain_scores_codex":[0.9996932,0.00005103834,0.00001732862,0.00002889673,0.00006090898,0.0001487515],"domain_scores_gemma":[0.9998059,0.00002914688,0.00003802322,0.00002755916,0.0000261771,0.0000731567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005257397,0.00005005687,0.001473827,0.0000661236,0.00001071505,0.000209066,0.0000364259,0.0003072617,0.9886453,0.0007165783,0.0004307497,0.00752817],"study_design_scores_gemma":[0.0001533741,0.0006618069,0.04904645,0.00005852787,0.00007471421,0.0008295304,0.0003309896,0.008998922,0.9299046,0.001464537,0.008440574,0.00003596946],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921206,0.001945992,0.001115803,0.0004164994,0.0001242696,0.00002287226,0.0002032506,0.00006135286,0.003989303],"genre_scores_gemma":[0.995944,0.0007417375,0.0006290778,0.0001706282,0.00003220105,0.00001129389,0.0002141734,0.00001698848,0.002239909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001786692,"threshold_uncertainty_score":0.005977035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009265780535470596,"score_gpt":0.2370047202166581,"score_spread":0.2277389396811875,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}