{"id":"W2105759732","doi":"10.1093/molbev/mss125","title":"Non Conservation of Function for the Evolutionarily Conserved Prdm1 Protein in the Control of the Slow Twitch Myogenic Program in the Mouse Embryo","year":2012,"lang":"en","type":"article","venue":"Molecular Biology and Evolution","topic":"Developmental Biology and Gene Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Centre National de la Recherche Scientifique; European Commission; Institut National de la Santé et de la Recherche Médicale; Institut national de la recherche scientifique","keywords":"Myotome; Myogenesis; MYF5; Biology; MyoD; Somite; Myogenic regulatory factors; Cell biology; Myogenin; Notochord; PAX3; Mesoderm; Myocyte; Embryo; Genetics; Embryonic stem cell; Embryogenesis; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001188499,0.0001162424,0.0001207925,0.00002962417,0.0001356021,0.000004453704,0.0001949253,0.0002398723,0.00000108918],"category_scores_gemma":[0.0001249193,0.00005864271,0.0000821372,0.0001753402,0.0003389874,0.000007770328,0.00003602571,0.0001072209,4.701203e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001724771,"about_ca_system_score_gemma":0.0000660543,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008173408,"about_ca_topic_score_gemma":0.0001757491,"domain_scores_codex":[0.9988365,0.0004398583,0.0002768687,0.0001672941,0.00007448096,0.0002049849],"domain_scores_gemma":[0.9994284,0.00006417483,0.0001713994,0.0002491638,0.00007532913,0.00001156961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0004353205,0.0001443271,0.1905758,0.00002314792,0.00005446142,5.355893e-8,0.0001304565,0.00005935758,0.8045989,0.002958043,0.0001398998,0.0008802303],"study_design_scores_gemma":[0.001270021,0.0004417318,0.9158022,0.0000147574,0.00005667657,0.0000105072,0.0003367769,0.0008687194,0.0780783,0.00143722,0.001578271,0.0001048084],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9847,0.002212651,0.009625529,0.001385003,0.00008819488,0.00194056,0.00001843568,0.000003149187,0.00002646777],"genre_scores_gemma":[0.9987131,0.000022599,0.0001235525,0.0003882273,0.00004098036,0.0005360689,0.00014289,0.000005365668,0.00002723587],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7265206,"threshold_uncertainty_score":0.239138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007461337637293847,"score_gpt":0.2423397657536328,"score_spread":0.234878428116339,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}