{"id":"W2105832153","doi":"10.1161/circresaha.110.219345","title":"Temporal and Spatial Regulation of Histone Deacetylase-7 and β-Catenin in Endothelial Cells","year":2010,"lang":"en","type":"letter","venue":"Circulation Research","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Histone deacetylase; Histone; Cell biology; Histone deacetylase 5; Cancer research; Biology; Chemistry; Medicine; Biochemistry; DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000406496,0.0002429508,0.0004088733,0.0002483454,0.0003939269,0.000712263,0.0005599489,0.001728136,0.002551849],"category_scores_gemma":[0.0008775832,0.0002467264,0.0003289253,0.0002158741,0.0005387238,0.0006682284,0.0002091671,0.00293977,0.000945365],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001402123,"about_ca_system_score_gemma":0.0002325908,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007129116,"about_ca_topic_score_gemma":0.00200978,"domain_scores_codex":[0.9997693,0.00004449566,0.00002547162,0.00003639452,0.00007336767,0.00005096445],"domain_scores_gemma":[0.9996424,0.0001498338,0.00005107957,0.00004974394,0.0000456821,0.0000612513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009270037,0.0005590361,0.005608375,0.0005322367,0.0001270383,0.01823169,0.0002948081,0.0007784817,0.7830096,0.01727236,0.09521086,0.06910545],"study_design_scores_gemma":[0.002034951,0.001560559,0.07475893,0.0001287279,0.0002288409,0.02088322,0.0007206281,0.008135107,0.5672466,0.01593219,0.3082457,0.0001246841],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5496354,0.04495743,0.008651275,0.3311785,0.02675154,0.0001385846,0.001125132,0.0004885913,0.03707352],"genre_scores_gemma":[0.9095161,0.0120603,0.003376402,0.03083171,0.01315117,0.0002148321,0.0003978092,0.00007545677,0.03037623],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002551849,"threshold_uncertainty_score":0.0101732,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02991312998145792,"score_gpt":0.3462462235029938,"score_spread":0.3163330935215359,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}