{"id":"W2105848478","doi":"10.1039/b812987h","title":"Real-time detection of the early event of cytotoxicity of herbal ingredients on single leukemia cells studied in a microfluidic biochip","year":2008,"lang":"en","type":"article","venue":"Integrative Biology","topic":"Microfluidic and Capillary Electrophoresis Applications","field":"Engineering","cited_by":37,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Natural Sciences and Engineering Research Council of Canada; Royal Society; Royal Society of Chemistry; Child and Family Research Institute","keywords":"Biochip; Cytotoxicity; Microfluidics; Chemistry; Leukemia; Biology; Nanotechnology; Biochemistry; In vitro; Bioinformatics; Immunology; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000228503,0.0003911568,0.0004785944,0.0002412224,0.0001750943,0.0003171324,0.0004728116,0.0003662897,0.000409457],"category_scores_gemma":[0.0003259385,0.0001658274,0.0001974814,0.000212058,0.0002845068,0.0003162572,0.0002288016,0.0003961491,0.000174388],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004839996,"about_ca_system_score_gemma":0.0002914392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003638973,"about_ca_topic_score_gemma":0.0005099251,"domain_scores_codex":[0.9998286,0.00001813146,0.0000150761,0.0000594687,0.00005401092,0.00002482575],"domain_scores_gemma":[0.9997892,0.00009433297,0.00004002126,0.00001746949,0.0000384011,0.00002062481],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003951351,0.00001181713,0.0001389999,0.00004380718,0.000003379123,0.00002188495,0.00001579528,0.0001330945,0.9965712,0.0001203236,0.00004569493,0.002854464],"study_design_scores_gemma":[0.00001000466,0.00009894429,0.0007666474,0.000002682683,0.000008404218,0.0000750022,0.000008694115,0.002764286,0.9950991,0.00004672745,0.001112324,0.000007220121],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8201239,0.006298748,0.1675902,0.000544094,0.0003362042,0.000278031,0.001163163,0.00120267,0.002463045],"genre_scores_gemma":[0.8531718,0.002433411,0.1414552,0.0002198174,0.00008735165,0.000385622,0.0003658127,0.00003595625,0.001845068],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004839996,"threshold_uncertainty_score":0.003511727,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009509511395515011,"score_gpt":0.2148244445203631,"score_spread":0.2053149331248481,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}