{"id":"W2105862640","doi":"10.1152/ajplung.00166.2007","title":"Contribution of xanthine oxidase-derived superoxide to chronic hypoxic pulmonary hypertension in neonatal rats","year":2007,"lang":"en","type":"article","venue":"American Journal of Physiology-Lung Cellular and Molecular Physiology","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre","funders":"Canadian Institutes of Health Research; National Institutes of Health; National Institute for Health and Care Research; Canadian Child Health Clinician Scientist Program","keywords":"Xanthine oxidase; Allopurinol; Hypoxia (environmental); Superoxide; Oxidative stress; Pulmonary hypertension; Endocrinology; Reactive oxygen species; Internal medicine; Nitrotyrosine; Lung; Xanthine; Chemistry; Mitochondrial ROS; Medicine; Nitric oxide; Biochemistry; Oxygen; Nitric oxide synthase; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005972254,0.0002824512,0.001203495,0.0004486642,0.0000429661,0.000003134571,0.0001665409,0.000137882,0.00001722096],"category_scores_gemma":[0.0002172787,0.0002320524,0.0002492228,0.0004676507,0.0004361862,0.00006975332,0.0001003032,0.0004404532,0.0000048969],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001117669,"about_ca_system_score_gemma":0.0001472709,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001098383,"about_ca_topic_score_gemma":0.000005277442,"domain_scores_codex":[0.9978671,0.0002723121,0.0007398673,0.0003606499,0.0002241286,0.0005359412],"domain_scores_gemma":[0.9984375,0.0002630247,0.000423807,0.000294534,0.0003008967,0.0002802238],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002517349,0.0002059885,0.0005002159,0.00007950664,0.0001569334,0.0006217968,0.0001244439,0.0001290808,0.9898849,0.00005918879,0.0000266245,0.005693936],"study_design_scores_gemma":[0.002152706,0.003567293,0.1001976,0.0001956882,0.0001500156,0.0006112474,0.0001842013,0.0003697741,0.8920484,0.0001896889,0.0001297557,0.0002036269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933839,0.003511514,0.002295033,0.0002936099,0.000162975,0.0003200014,0.000004546891,0.00001301291,0.00001535524],"genre_scores_gemma":[0.9978289,0.0003330132,0.0006902751,0.0008574686,0.0002136338,0.000004045182,0.00003317075,0.00003379588,0.000005710775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09969741,"threshold_uncertainty_score":0.9462821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004347617696174685,"score_gpt":0.2331276412147459,"score_spread":0.2287800235185712,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}