{"id":"W2105883156","doi":"10.1038/srep03664","title":"A new paradigm for transcription factor TFIIB functionality","year":2014,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec; Centre hospitalier universitaire de Québec","funders":"National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute","keywords":"Transcription factor II B; Transcription factor II A; RNA polymerase II; Transcription preinitiation complex; Promoter; Transcription factor II D; Biology; Transcription (linguistics); Transcription factor; Gene knockdown; General transcription factor; Cell biology; Genetics; Transcription factor II F; Gene; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007619612,0.0002907429,0.0004636134,0.0003427831,0.0004207169,0.001065208,0.0005294802,0.0006687132,0.001322078],"category_scores_gemma":[0.0004376053,0.0001507941,0.0002745994,0.0001885782,0.001939424,0.00184982,0.0004462522,0.001355407,0.0004509462],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000965376,"about_ca_system_score_gemma":0.0005367407,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000427873,"about_ca_topic_score_gemma":0.0003629714,"domain_scores_codex":[0.9996762,0.00004420317,0.00001405132,0.000141144,0.00007538469,0.00004898821],"domain_scores_gemma":[0.9997136,0.00007624133,0.00002692155,0.00007349804,0.00005043071,0.00005934777],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001964579,0.0000150305,0.0007183207,0.0001528646,0.0000110799,0.0001260088,0.0003163145,0.0002626079,0.9027079,0.07138014,0.000590846,0.02352243],"study_design_scores_gemma":[0.00009174066,0.0008418873,0.009412021,0.0001651932,0.00008044059,0.00236849,0.0007507622,0.008141675,0.5696096,0.1676924,0.2407438,0.0001018457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4738139,0.07034668,0.4003957,0.02313771,0.001335649,0.00004450946,0.0007724287,0.001808482,0.02834499],"genre_scores_gemma":[0.9414722,0.01115139,0.03666614,0.002356528,0.0004839067,0.00006840601,0.000349191,0.000180451,0.00727172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001322078,"threshold_uncertainty_score":0.007004321,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01269856934346015,"score_gpt":0.232552377917194,"score_spread":0.2198538085737338,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}