{"id":"W2105910778","doi":"10.1164/rccm.200906-0925oc","title":"Activating Transcription Factor 3 Confers Protection against Ventilator-induced Lung Injury","year":2010,"lang":"en","type":"article","venue":"American Journal of Respiratory and Critical Care Medicine","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University Health Network; St. Michael's Hospital","funders":"National Cancer Institute; National Institutes of Health","keywords":"ATF3; Proinflammatory cytokine; Activating transcription factor; Medicine; Bronchoalveolar lavage; Lung; Inflammation; Transcription factor; Pulmonary edema; Mechanical ventilation; In vivo; Immunology; Respiratory distress; Gene expression; Biology; Gene; Anesthesia; Promoter; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001504088,0.0003827861,0.0002949034,0.0002616863,0.0001306611,0.0001831717,0.000250467,0.000347643,0.003240763],"category_scores_gemma":[0.0002051498,0.0000917801,0.0003008566,0.0001591761,0.0002557256,0.0001482681,0.0002028196,0.00065031,0.0003875763],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001540193,"about_ca_system_score_gemma":0.0001930695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001846002,"about_ca_topic_score_gemma":0.0002117993,"domain_scores_codex":[0.9999237,0.00001332358,0.000006860223,0.00001498588,0.00001650103,0.00002460278],"domain_scores_gemma":[0.9997769,0.00003183828,0.00007267518,0.00002013488,0.00001522951,0.00008315359],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002021093,0.0001740948,0.001527969,0.0001024504,0.00002104015,0.0001188135,0.00001155966,0.00007241913,0.9919125,0.00008535257,0.0001328863,0.003819754],"study_design_scores_gemma":[0.0004830632,0.008878459,0.06555688,0.00007310378,0.0002060305,0.004142364,0.0001023901,0.002124473,0.9113058,0.0005116665,0.006590496,0.00002521065],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955799,0.001207312,0.001613695,0.0001956107,0.00006074439,0.00002487395,0.0004560052,0.0001154974,0.0007462875],"genre_scores_gemma":[0.9961591,0.0006626619,0.001270467,0.00010368,0.00002370401,0.00003670463,0.0009055113,0.00001896447,0.0008190976],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003240763,"threshold_uncertainty_score":0.01084143,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01750419232745371,"score_gpt":0.2934632076650516,"score_spread":0.2759590153375979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}