{"id":"W2105918195","doi":"10.1128/aem.01642-10","title":"Characterization of a Phosphotriesterase-Like Lactonase from <i>Sulfolobus solfataricus</i> and Its Immobilization for Disruption of Quorum Sensing","year":2010,"lang":"en","type":"article","venue":"Applied and Environmental Microbiology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Homoserine; Quorum sensing; Sulfolobus solfataricus; Quorum Quenching; Pyocyanin; Chemistry; Biochemistry; Pseudomonas putida; Enzyme; Virulence; Microbiology; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001675409,0.0006677328,0.0003794479,0.0002309469,0.0001267242,0.0003830713,0.0002816098,0.0003840504,0.0005478802],"category_scores_gemma":[0.0002856059,0.0001366861,0.0003914614,0.0003158657,0.0002070771,0.0003113532,0.0003049198,0.0003770321,0.0003670476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002633006,"about_ca_system_score_gemma":0.000210153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001420841,"about_ca_topic_score_gemma":0.001068318,"domain_scores_codex":[0.9998763,0.00001706576,0.00001510663,0.00002243682,0.00004708131,0.00002197668],"domain_scores_gemma":[0.9998542,0.0000278735,0.00004151057,0.00001526413,0.00002923169,0.00003191194],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002537765,0.00001375762,0.0002083279,0.00002975795,0.000004370534,0.00002738637,0.00001121787,0.00003392694,0.9987863,0.00001561139,0.00001238238,0.0008316009],"study_design_scores_gemma":[0.000008679791,0.0001689728,0.0076503,0.000008390924,0.00002239014,0.0003648696,0.00005355546,0.0007328283,0.9885442,0.00002087279,0.002416039,0.000008818084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9945991,0.0007761857,0.003416117,0.0001471518,0.00001878785,0.0000406846,0.0005009413,0.00006819181,0.0004328639],"genre_scores_gemma":[0.9866405,0.0008162116,0.006480633,0.00006716634,0.00001687677,0.00007087728,0.00357029,0.0000460148,0.002291503],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001420841,"threshold_uncertainty_score":0.002825141,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003725446338107841,"score_gpt":0.1760428285649719,"score_spread":0.1723173822268641,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}