{"id":"W2106015219","doi":"10.1016/j.ahj.2013.03.003","title":"A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: Design of the RENEW study","year":2013,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Pain Management and Treatment","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Cardiovascular Society","keywords":"Medicine; Refractory (planetary science); Angina; Randomized controlled trial; Surgery; Internal medicine; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004232795,0.001702186,0.00477124,0.0006234355,0.0007770516,0.001060372,0.001394379,0.002867923,0.004216405],"category_scores_gemma":[0.004690719,0.0007652175,0.001728583,0.0004826174,0.002154788,0.001222006,0.0004959913,0.003565613,0.0009065359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006553924,"about_ca_system_score_gemma":0.001990077,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004908038,"about_ca_topic_score_gemma":0.001072723,"domain_scores_codex":[0.9979067,0.001224719,0.000148423,0.0003334276,0.0001701666,0.0002165816],"domain_scores_gemma":[0.9972656,0.0009912382,0.000532276,0.0004593694,0.0002236306,0.0005279472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9744251,0.01128544,0.0004064127,0.0002735645,0.0004463098,0.00002261805,0.00005560711,0.0002186422,0.003650083,0.0001339286,0.0003774859,0.008704844],"study_design_scores_gemma":[0.9420756,0.0562204,0.0006921875,0.000009004613,0.0001608638,0.00001170166,0.000008552335,0.0002044338,0.0003220742,0.00009487609,0.0001897988,0.00001053399],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"protocol","genre_scores_codex":[0.9756407,0.001502233,0.002659101,0.0003840424,0.0004546781,0.01621983,0.0009426523,0.0002801816,0.001916709],"genre_scores_gemma":[0.9598009,0.001006899,0.00952829,0.002050822,0.0008026065,0.02373482,0.001018942,0.00007568192,0.001981005],"genre_candidate":"protocol","genre_consensus":null,"teacher_disagreement_score":0.00477124,"threshold_uncertainty_score":0.02238542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192885636019649,"score_gpt":0.3240450320230712,"score_spread":0.3047564684211063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}