{"id":"W2106015219","doi":"10.1016/j.ahj.2013.03.003","title":"A phase 3, randomized, double-blinded, active-controlled, unblinded standard of care study assessing the efficacy and safety of intramyocardial autologous CD34+ cell administration in patients with refractory angina: Design of the RENEW study","year":2013,"lang":"en","type":"article","venue":"American Heart Journal","topic":"Pain Management and Treatment","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Cardiovascular Society","keywords":"Medicine; Refractory (planetary science); Angina; Randomized controlled trial; Surgery; Internal medicine; Myocardial infarction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001249387,0.0001857757,0.001251097,0.0001708311,0.000123106,0.00003092604,0.00009825015,0.00002766832,0.000009831249],"category_scores_gemma":[0.0001378964,0.00008983509,0.0001381695,0.0003385514,0.0003575029,0.0001279932,0.0000343727,0.0002770122,1.892584e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067173,"about_ca_system_score_gemma":0.0003464369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002151651,"about_ca_topic_score_gemma":0.00002256098,"domain_scores_codex":[0.9969419,0.001426447,0.0006987187,0.0001795177,0.0005694575,0.0001839386],"domain_scores_gemma":[0.9977418,0.0007151673,0.0008320676,0.0002813229,0.0003593666,0.00007025022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.6144777,0.008641306,0.35465,0.00002875836,0.001204324,0.00001544537,0.005670478,0.0001383763,0.000117427,0.000001962752,0.00001782444,0.01503645],"study_design_scores_gemma":[0.5470158,0.01804567,0.4199767,0.00009025958,0.001016547,0.000005146455,0.01354231,0.00005156808,0.0001801642,0.000004340639,0.000003096672,0.00006845142],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9918827,0.0001216806,0.0004006044,0.000227171,0.000048629,0.007230828,0.000003124264,0.000005399221,0.00007990302],"genre_scores_gemma":[0.9992363,0.00002263407,0.0005921515,0.00002558418,0.00002803422,0.00007347011,0.000002025203,0.00001403483,0.00000571851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06746191,"threshold_uncertainty_score":0.3663369,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192885636019649,"score_gpt":0.3240450320230712,"score_spread":0.3047564684211063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}