{"id":"W2106026940","doi":"10.1016/j.taap.2013.09.020","title":"A role for glutathione, independent of oxidative stress, in the developmental toxicity of methanol","year":2013,"lang":"en","type":"article","venue":"Toxicology and Applied Pharmacology","topic":"Prenatal Substance Exposure Effects","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Glutathione; Oxidative stress; Chemistry; Buthionine sulfoximine; In vivo; Teratology; Reactive oxygen species; Toxicity; Deoxyguanosine; Biochemistry; Pharmacology; Andrology; Fetus; Biology; Medicine; Pregnancy; Genetics; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000234506,0.0003763436,0.0001998,0.0004556027,0.0003891994,0.0002761339,0.0003877559,0.0006038916,0.001278426],"category_scores_gemma":[0.0004227951,0.0001722986,0.0002665333,0.0001512518,0.0005776451,0.0004541152,0.0004422073,0.0004394427,0.00014322],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000491523,"about_ca_system_score_gemma":0.000897728,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001690488,"about_ca_topic_score_gemma":0.003268319,"domain_scores_codex":[0.999891,0.00003331515,0.00001149268,0.00002085314,0.00002196865,0.00002142418],"domain_scores_gemma":[0.999645,0.00007359708,0.00008486035,0.00006557207,0.00006635133,0.00006455497],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00123022,0.00008869751,0.003671611,0.0002644967,0.00005267054,0.0009463098,0.000222845,0.0001460482,0.9772335,0.005296932,0.0001575738,0.01068907],"study_design_scores_gemma":[0.00005247975,0.001155513,0.02611215,0.00006444024,0.0001221623,0.001136723,0.0002709806,0.0004419535,0.9644335,0.002112322,0.00408071,0.00001710495],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9778998,0.009856066,0.006683493,0.001019227,0.00008048295,0.00003362165,0.0002977096,0.000122605,0.004006993],"genre_scores_gemma":[0.9934068,0.002530548,0.001871764,0.00007079719,0.00001143702,0.0000189398,0.0001203222,0.000008059992,0.001961304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001690488,"threshold_uncertainty_score":0.004276752,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433743972397624,"score_gpt":0.2875867904340588,"score_spread":0.2732493507100826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}