{"id":"W2106099541","doi":"10.1677/joe.0.1740017","title":"Failed export of the adrenocorticotrophin receptor from the endoplasmic reticulum in non-adrenal cells: evidence in support of a requirement for a specific adrenal accessory factor","year":2002,"lang":"en","type":"article","venue":"Journal of Endocrinology","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; University of Toronto; National Institutes of Health; Queen Mary University of London","keywords":"KDEL; Transfection; Endoplasmic reticulum; Green fluorescent protein; Receptor; Melanocortin; ACTH receptor; Biology; Cell biology; Cell culture; Adrenocorticotropic hormone; Molecular biology; Endocrinology; Hormone; Gene; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000484592,0.0003995771,0.0005118628,0.0001739819,0.0002543164,0.0009154214,0.0005692656,0.0005594277,0.001453062],"category_scores_gemma":[0.0004029541,0.0002255365,0.0005352841,0.0002045034,0.0003611546,0.0005999511,0.0005198315,0.0009172143,0.001817267],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003202237,"about_ca_system_score_gemma":0.0003173,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009729179,"about_ca_topic_score_gemma":0.001132841,"domain_scores_codex":[0.999608,0.00005780477,0.00007948338,0.00007874211,0.0001187834,0.00005726251],"domain_scores_gemma":[0.9992208,0.000175371,0.0001032854,0.000261306,0.0001219993,0.000117157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004757223,0.000008499195,0.0001721698,0.00003233766,0.000003999488,0.0001449338,0.00002366464,0.000008800624,0.9991965,0.00005357067,0.00001434605,0.0002936372],"study_design_scores_gemma":[0.00002324698,0.0001440858,0.01128497,0.00001066612,0.00002170064,0.001850081,0.0001527506,0.0005395317,0.9822953,0.0000767297,0.003588176,0.00001277587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9791739,0.00326275,0.01372081,0.0003475994,0.0001395245,0.00004310285,0.001149361,0.0002324833,0.001930534],"genre_scores_gemma":[0.9811826,0.001653364,0.008273956,0.0001609356,0.00002674378,0.00006422257,0.002811843,0.0002197536,0.005606512],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001453062,"threshold_uncertainty_score":0.004860997,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04909322745997109,"score_gpt":0.2671231366176756,"score_spread":0.2180299091577045,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}