{"id":"W2106123323","doi":"10.1128/aac.46.6.2041-2045.2002","title":"Lentivirus Lytic Peptide 1 Perturbs both Outer and Inner Membranes of <i>Serratia marcescens</i>","year":2002,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Children's Hospital of Pittsburgh; National Institute of Arthritis and Musculoskeletal and Skin Diseases; University of Pittsburgh; National Institutes of Health; Cystic Fibrosis Foundation","keywords":"Serratia marcescens; Lytic cycle; Bacterial outer membrane; Polymyxin; Polymyxin B; Microbiology; Cytoplasm; Membrane; Peptide; Biology; Electron microscope; Inner membrane; Chemistry; Biochemistry; Virology; Escherichia coli; Virus; Antibiotics; Physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001480971,0.000288113,0.0001283505,0.0001026382,0.00009167347,0.0002424105,0.0001364113,0.0002309267,0.0004204283],"category_scores_gemma":[0.0001424502,0.0001110142,0.000136973,0.00006844819,0.0002003742,0.0002070673,0.0001521663,0.0004006516,0.0001843216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002877509,"about_ca_system_score_gemma":0.0001358771,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007818693,"about_ca_topic_score_gemma":0.0006060136,"domain_scores_codex":[0.9999094,0.00001482767,0.000007865232,0.00001438082,0.00002739417,0.00002612133],"domain_scores_gemma":[0.9998777,0.00002200971,0.000052455,0.000009205231,0.00001320579,0.00002535779],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000202208,0.000005035261,0.00009577083,0.000008403366,0.000001204428,0.00002161377,0.000004923449,0.00001329737,0.9995691,0.00002779981,0.000005348702,0.0002272778],"study_design_scores_gemma":[0.000009125591,0.000161131,0.0040455,0.000003071206,0.000007621881,0.0002342271,0.00001999716,0.0003738021,0.9944304,0.00002798741,0.0006846518,0.000002546062],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977381,0.0004194555,0.001160368,0.00003876577,0.000008737097,0.000008242839,0.00005770071,0.00002660448,0.0005419558],"genre_scores_gemma":[0.9974853,0.0003441217,0.001198761,0.00004768445,0.000005034313,0.00001067315,0.0001892353,0.000009535071,0.0007096746],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007818693,"threshold_uncertainty_score":0.002087831,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01541691212290252,"score_gpt":0.212920995048278,"score_spread":0.1975040829253755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}