{"id":"W2106127270","doi":"10.1074/mcp.m400182-mcp200","title":"Proteome Dynamics during C2C12 Myoblast Differentiation","year":2005,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":147,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"C2C12; Myogenesis; Proteome; Biology; Myocyte; Skeletal muscle; Cell biology; Computational biology; Transcriptome; Cellular differentiation; Gene expression; Bioinformatics; Genetics; Gene; Anatomy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001401029,0.000183756,0.0002536089,0.000427453,0.0002773699,0.0005059289,0.0001582538,0.0002166044,0.0004975966],"category_scores_gemma":[0.0002021096,0.0001566624,0.000125572,0.0004434084,0.0002148355,0.0002256755,0.0002499319,0.0003891803,0.0003053923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00044222,"about_ca_system_score_gemma":0.0002616726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002551009,"about_ca_topic_score_gemma":0.003581682,"domain_scores_codex":[0.9998994,0.000007157302,0.000005282731,0.0000292212,0.00004104408,0.00001802355],"domain_scores_gemma":[0.9998883,0.00001851329,0.00002254692,0.000005330628,0.00003634204,0.00002899162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001487138,0.000008237215,0.001378621,0.0000393728,0.000007939117,0.00005467593,0.00007023012,0.00008780566,0.9962543,0.00006258877,0.00007364344,0.001813825],"study_design_scores_gemma":[0.00001743541,0.0001571711,0.1811363,0.00002406924,0.00004063213,0.0003235109,0.0002968417,0.00309389,0.8104901,0.0001747232,0.004216779,0.00002852877],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948666,0.001157899,0.001784278,0.00005522883,0.000007682333,0.00001156537,0.001188322,0.00005170901,0.0008766672],"genre_scores_gemma":[0.9886711,0.001602404,0.003192586,0.0001079773,0.000009187515,0.00006474878,0.002835534,0.00004703898,0.00346942],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002551009,"threshold_uncertainty_score":0.005072355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002658611691218691,"score_gpt":0.1892939599591118,"score_spread":0.1866353482678931,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}