{"id":"W2106314180","doi":"10.1093/annonc/mdq309","title":"Comorbidity, age and overall survival in cetuximab-treated patients with advanced colorectal cancer (ACRC)—results from NCIC CTG CO.17: a phase III trial of cetuximab versus best supportive care","year":2010,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Colorectal Cancer Treatments and Studies","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Thunder Bay Regional Health Sciences Centre; Ottawa Hospital","funders":"","keywords":"Medicine; Comorbidity; Internal medicine; Cetuximab; Univariate analysis; Hazard ratio; Proportional hazards model; Multivariate analysis; Cancer; Gastroenterology; Colorectal cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001311962,0.0002962339,0.001306788,0.000141593,0.00006092933,0.000005971681,0.00009802812,0.0002039508,0.00009174109],"category_scores_gemma":[0.0001911726,0.0002305282,0.0001063595,0.0001815491,0.0004516083,0.00009412582,0.00008564456,0.000305588,0.000001129043],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001423629,"about_ca_system_score_gemma":0.0004056888,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.008568173,"about_ca_topic_score_gemma":0.03961992,"domain_scores_codex":[0.9981199,0.00009242538,0.0006261989,0.0004632935,0.0003231684,0.0003750455],"domain_scores_gemma":[0.9981732,0.0004483439,0.0004786949,0.0002151874,0.0005348732,0.0001497023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8648487,0.007425051,0.0633009,0.00005736967,0.0008878227,0.0004011444,0.005395279,0.000003905204,0.002390285,0.00001056011,0.0005729846,0.05470598],"study_design_scores_gemma":[0.6425953,0.08143172,0.2615057,0.0001249737,0.0004220684,0.000002209951,0.001357809,0.00001008799,0.009200179,0.00001752256,0.00305039,0.0002820633],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886878,0.0003329551,2.366698e-7,0.0003034859,0.0005908257,0.001370307,0.002446759,0.00001694625,0.006250756],"genre_scores_gemma":[0.9982067,0.0005923579,0.00007411303,0.00007135278,0.000104146,0.000137924,0.000740716,0.00002285883,0.0000497672],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2222534,"threshold_uncertainty_score":0.9980339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05681807282855239,"score_gpt":0.3986025288890949,"score_spread":0.3417844560605425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}