{"id":"W2106319740","doi":"10.1128/aac.44.3.763-766.2000","title":"Iron-Chelating Activity of Tetracyclines and Its Impact on the Susceptibility of <i>Actinobacillus actinomycetemcomitans</i> to These Antibiotics","year":2000,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Oral microbiology and periodontitis research","field":"Dentistry","cited_by":92,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Minocycline; Doxycycline; Actinobacillus; Deferoxamine; Tetracycline; Antibiotics; Microbiology; Siderophore; Tetracycline antibiotics; Chemistry; Chelation; Biology; Bacteria; Biochemistry; Inorganic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002619757,0.0003269032,0.0004129786,0.0002606088,0.0002158973,0.0004195631,0.0001994241,0.0003049332,0.0008228217],"category_scores_gemma":[0.0007618099,0.0001708596,0.0002058957,0.0002422555,0.0001802492,0.0001923943,0.0001875662,0.000300307,0.0001745806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000257879,"about_ca_system_score_gemma":0.0002675024,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003422089,"about_ca_topic_score_gemma":0.003225523,"domain_scores_codex":[0.999564,0.000113885,0.00005634425,0.0000554244,0.000120793,0.00008948043],"domain_scores_gemma":[0.9994798,0.0001555446,0.0001074527,0.000044639,0.0001370172,0.00007556241],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000340245,0.0001108748,0.001220756,0.0000516127,0.00000825304,0.00006128908,0.00003592205,0.00007902208,0.9958929,0.00002448742,0.00004493972,0.002129567],"study_design_scores_gemma":[0.00002259829,0.001888731,0.0367688,0.00002131446,0.00003823738,0.0003577615,0.0001253706,0.0007135358,0.9587891,0.00003549655,0.001223997,0.00001504688],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983013,0.0006681,0.0001475328,0.00004333262,0.000009819389,0.0000100717,0.0002091999,0.00001384451,0.0005967106],"genre_scores_gemma":[0.9979488,0.0003352604,0.0006458671,0.00002504142,0.0000100987,0.00001081809,0.0004599913,0.000007248666,0.0005567313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003422089,"threshold_uncertainty_score":0.006804347,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02407848756445588,"score_gpt":0.3203442308322684,"score_spread":0.2962657432678125,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}