{"id":"W2106379961","doi":"10.3816/clm.2008.n.051","title":"Pegylated Liposomal Doxorubicin plus Bortezomib in Relapsed or Refractory Multiple Myeloma: Efficacy and Safety in Patients with Renal Function Impairment","year":2008,"lang":"en","type":"article","venue":"Clinical Lymphoma & Myeloma","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hotel Dieu Hospital; Leukemia & Lymphoma Society of Canada","funders":"","keywords":"Bortezomib; Medicine; Multiple myeloma; Refractory (planetary science); Oncology; Doxorubicin; Internal medicine; Renal function; Chemotherapy; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005881237,0.0003739072,0.001159223,0.0002700707,0.0001981986,0.0003990434,0.0002722218,0.0003423143,0.001028498],"category_scores_gemma":[0.0009181521,0.000170098,0.0004651089,0.0003921403,0.0003243511,0.0004824327,0.0002047383,0.0008852354,0.0002242106],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006027648,"about_ca_system_score_gemma":0.0004589425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008502006,"about_ca_topic_score_gemma":0.00103836,"domain_scores_codex":[0.9998205,0.00007764836,0.00001237904,0.00003142039,0.00002210734,0.00003593855],"domain_scores_gemma":[0.9996389,0.0001090099,0.00008952128,0.00002765628,0.00001342059,0.0001214998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5487207,0.007111924,0.04925119,0.0006362724,0.001602754,0.000738141,0.0003413971,0.003698947,0.03046663,0.0002695252,0.00173319,0.3554293],"study_design_scores_gemma":[0.2427171,0.3822308,0.3379129,0.0001632418,0.002986709,0.002602978,0.0003393515,0.01020061,0.01483535,0.0005668735,0.005338627,0.0001054778],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962759,0.002941769,0.0001104446,0.0001198472,0.00001746781,0.00003851432,0.00008112821,0.0000197407,0.0003952275],"genre_scores_gemma":[0.9987087,0.0008107361,0.000109579,0.00007173143,0.00003292756,0.0000225019,0.00009137557,0.000003510164,0.0001487858],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001159223,"threshold_uncertainty_score":0.004373372,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03079867005749204,"score_gpt":0.3048801949785689,"score_spread":0.2740815249210768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}