{"id":"W2106392984","doi":"10.1139/bcb-2013-0106","title":"Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agencia Nacional de Promoción Científica y Tecnológica; Universidad Nacional del Sur; National Cancer Institute; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Cell cycle; Cyclin D1; Cyclin D3; PI3K/AKT/mTOR pathway; Protein kinase B; MAPK/ERK pathway; Cancer research; Cyclin; Biology; Cell biology; Cyclin-dependent kinase 2; Signal transduction; Kinase; Chemistry; Cell; Protein kinase A; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139268,0.0004373033,0.0002434874,0.0003965022,0.0002999911,0.0002334802,0.0001360207,0.0001948464,0.0006457397],"category_scores_gemma":[0.00007043821,0.0001777733,0.0003703544,0.0002186349,0.0001687078,0.00026136,0.0001652656,0.000402276,0.0001893692],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000259968,"about_ca_system_score_gemma":0.0003812108,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001072858,"about_ca_topic_score_gemma":0.001093634,"domain_scores_codex":[0.9999182,0.00001209315,0.000008665374,0.00001436562,0.00002220205,0.00002442982],"domain_scores_gemma":[0.9999706,0.000003287857,0.000007826027,0.000002816631,0.000006755793,0.000008656296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007671558,0.0001348495,0.00134258,0.0002237663,0.00001519555,0.0002696433,0.00005728704,0.0002050671,0.9909518,0.0002479876,0.0001019994,0.005682598],"study_design_scores_gemma":[0.0002774571,0.0008357799,0.07965557,0.00002668983,0.00009213196,0.00124091,0.000139011,0.005602234,0.9042998,0.0005443902,0.007260049,0.00002588683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812316,0.01285296,0.002481449,0.0002279035,0.00005857636,0.00007607945,0.0005615343,0.00007830927,0.002431529],"genre_scores_gemma":[0.9882863,0.006593071,0.002342855,0.00008407304,0.00002195363,0.0001252583,0.0005380733,0.000007245859,0.002001122],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001072858,"threshold_uncertainty_score":0.002160192,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008511899470856087,"score_gpt":0.2205637122578715,"score_spread":0.2120518127870154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}