{"id":"W2106392984","doi":"10.1139/bcb-2013-0106","title":"Involvement of ERK1/2, p38 MAPK, and PI3K/Akt signaling pathways in the regulation of cell cycle progression by PTHrP in colon adenocarcinoma cells","year":2014,"lang":"en","type":"article","venue":"Biochemistry and Cell Biology","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Agencia Nacional de Promoción Científica y Tecnológica; Universidad Nacional del Sur; National Cancer Institute; Consejo Nacional de Investigaciones Científicas y Técnicas","keywords":"Cell cycle; Cyclin D1; Cyclin D3; PI3K/AKT/mTOR pathway; Protein kinase B; MAPK/ERK pathway; Cancer research; Cyclin; Biology; Cell biology; Cyclin-dependent kinase 2; Signal transduction; Kinase; Chemistry; Cell; Protein kinase A; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003400489,0.0001214074,0.0002396764,0.00004397326,0.00002105453,0.000003102185,0.00006813258,0.0002472602,0.00001416993],"category_scores_gemma":[0.00002025253,0.00009487326,0.00002687208,0.000111636,0.0001522201,0.0000110528,0.0000454125,0.0001510625,4.394901e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002719724,"about_ca_system_score_gemma":0.00004598909,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004372,"about_ca_topic_score_gemma":0.000005076015,"domain_scores_codex":[0.9990858,0.00008825204,0.0003124826,0.0002661793,0.00008680306,0.0001604444],"domain_scores_gemma":[0.9994792,0.00007676127,0.0001749459,0.0001962684,0.00002967266,0.00004317227],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001655974,0.0002076007,0.006108319,0.0004919933,0.00000472293,0.000002307462,0.0003670135,0.000006851149,0.9913815,0.00001462678,0.0000636622,0.001185809],"study_design_scores_gemma":[0.00189597,0.0005689035,0.001651672,0.0001740454,0.00002485348,0.00000398844,0.0002814407,0.0002605742,0.9947159,0.00009927074,0.000236836,0.00008654949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944804,0.00426515,0.0000357415,0.000057063,0.00002757725,0.0002849688,0.00001653761,0.000005450604,0.0008271401],"genre_scores_gemma":[0.9994226,0.0001592029,0.0001834935,0.00005410433,0.00002557221,0.00001676467,0.0001001312,0.000008064025,0.00003003523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00494226,"threshold_uncertainty_score":0.3868819,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008511899470856087,"score_gpt":0.2205637122578715,"score_spread":0.2120518127870154,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}