{"id":"W2106400778","doi":"10.1083/jcb.149.7.1473","title":"Apical Membrane Targeting of Nedd4 Is Mediated by an Association of Its C2 Domain with Annexin Xiiib","year":2000,"lang":"en","type":"article","venue":"The Journal of Cell Biology","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":146,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"NEDD4; Annexin A2; Annexin; Apical membrane; C2 domain; Biology; Cell biology; Colocalization; Ubiquitin ligase; WW domain; Immunogold labelling; Molecular biology; Biochemistry; Ubiquitin; Cell; Membrane; Antibody","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009296568,0.000103877,0.0002460104,0.00002939922,0.00003801512,0.000002942226,0.0002419332,0.0002028411,0.0003189126],"category_scores_gemma":[0.00008089947,0.00006438143,0.00006637179,0.00007532247,0.00008674014,0.000005162803,0.0000211989,0.0001525614,0.000003384573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001625663,"about_ca_system_score_gemma":0.00008031942,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009075612,"about_ca_topic_score_gemma":0.000004786927,"domain_scores_codex":[0.9987486,0.0004560251,0.000397054,0.00009679396,0.0001228872,0.0001786316],"domain_scores_gemma":[0.9989876,0.00007868248,0.0005728378,0.0001261139,0.0001625324,0.00007224382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000752807,0.00008647102,0.0005739072,0.00001790134,0.00006646875,8.800596e-7,0.0002676898,0.00003002731,0.9972252,0.00001090444,0.0006886476,0.0002790623],"study_design_scores_gemma":[0.0008907332,0.001738983,0.00007666951,0.00001023449,0.00003237277,0.00001640386,0.0001284398,0.00002593927,0.9852533,0.0001259833,0.01162386,0.00007710671],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968392,0.001132644,0.0001987767,0.0003983104,0.00003551638,0.00008859584,0.00006143068,0.000002103662,0.001243479],"genre_scores_gemma":[0.9978374,0.001098766,0.0003810894,0.0002620415,0.0001208847,9.880989e-7,0.0000526143,0.00001049795,0.0002356706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01197196,"threshold_uncertainty_score":0.349187,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005803947186251651,"score_gpt":0.2206037884899625,"score_spread":0.2147998413037109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}