{"id":"W2106431826","doi":"10.1172/jci64560","title":"HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates","year":2012,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Maple Leaf Medical Clinic; Simon Fraser University; St. Michael's Hospital","funders":"National Institute of Allergy and Infectious Diseases; Ontario HIV Treatment Network; Ontario Innovation Trust; National Institutes of Health; Pfizer","keywords":"Biology; Virology; Cytotoxic T cell; CD8; Simian immunodeficiency virus; Immune system; T cell; Long terminal repeat; Antigen; Virus; Genome; In vitro; Immunology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001446442,0.0004048829,0.0003638923,0.000126656,0.0001366944,0.0003198021,0.0002908968,0.0003326182,0.00190275],"category_scores_gemma":[0.0001376411,0.0001054248,0.0003138462,0.0000548231,0.000164891,0.0001991854,0.0002425744,0.000911603,0.0004506361],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001562105,"about_ca_system_score_gemma":0.0001804453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001935172,"about_ca_topic_score_gemma":0.0004421152,"domain_scores_codex":[0.9997806,0.00002697152,0.00001220468,0.00005300706,0.00003104112,0.00009633123],"domain_scores_gemma":[0.9999075,0.00002249983,0.00001322513,0.00002001409,0.00001328063,0.00002346799],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201946,0.0001517239,0.0006954223,0.0000530405,0.00001171198,0.0001025689,0.00005191509,0.000365215,0.9896957,0.0001584461,0.0000964709,0.008415926],"study_design_scores_gemma":[0.0002252049,0.003658317,0.007792851,0.00004505885,0.00007134477,0.001662069,0.0001623816,0.003747084,0.9738033,0.0005517344,0.008267536,0.00001299674],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9952145,0.0005918557,0.002334157,0.00005290571,0.00002563758,0.00006681348,0.00007179808,0.0000597779,0.001582492],"genre_scores_gemma":[0.9951793,0.0003456278,0.00168,0.0001237975,0.000040191,0.0000441023,0.0001902335,0.00001549028,0.002381227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00190275,"threshold_uncertainty_score":0.006365359,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07784058759385254,"score_gpt":0.2911674121585729,"score_spread":0.2133268245647204,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}