{"id":"W2106432355","doi":"10.1016/j.tcm.2010.09.002","title":"Cholesterol Homeostasis and High-Density Lipoprotein Formation in Arterial Smooth Muscle Cells","year":2010,"lang":"en","type":"review","venue":"Trends in Cardiovascular Medicine","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Paul's Hospital; Providence Health Care","funders":"Canadian Institutes of Health Research; Heart and Stroke Foundation of Canada","keywords":"Cholesterol; Atheroma; Homeostasis; Foam cell; ABCA1; High-density lipoprotein; Cell biology; Macrophage; Lipoprotein; Biology; Reverse cholesterol transport; Internal medicine; Endocrinology; Chemistry; Biochemistry; Transporter; Medicine; In vitro; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001519904,0.000707964,0.004104986,0.0008845069,0.00009742403,0.00002670582,0.0003492436,0.001125168,0.0002225497],"category_scores_gemma":[0.00006574232,0.0005542859,0.001633106,0.0006323023,0.0004130191,0.000151409,0.0001767751,0.001149334,0.00007011906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001399559,"about_ca_system_score_gemma":0.00004548007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001505419,"about_ca_topic_score_gemma":0.0004803811,"domain_scores_codex":[0.9962158,0.00109631,0.0009911875,0.0008860804,0.0002354925,0.0005751619],"domain_scores_gemma":[0.9981876,0.00008575599,0.0002610963,0.001341188,0.00004651182,0.0000778412],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000143044,0.0000673372,0.000002300755,0.001240396,0.0007473796,0.00003549999,0.0001694383,0.000001621526,0.0002258371,0.000006627981,0.0001750806,0.9973142],"study_design_scores_gemma":[0.004474615,0.0001060011,0.009898535,0.005456783,0.003103083,0.0001056365,0.00008257812,4.947461e-7,0.0001168144,0.00001072097,0.9760519,0.0005928679],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005514355,0.9919687,0.00007361673,0.0000264272,0.001402752,0.0007118126,0.00009516093,0.0000585152,0.0001486823],"genre_scores_gemma":[0.02445969,0.9738985,0.00002348655,0.00003123056,0.0003774165,0.0002383435,0.0008458924,0.00007774205,0.00004767844],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9967213,"threshold_uncertainty_score":0.9996909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02580289242970496,"score_gpt":0.2643600560130674,"score_spread":0.2385571635833624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}