{"id":"W2106471696","doi":"10.1039/c5md00189g","title":"Enhanced in vitro and in vivo uptake of a hydrophobic model drug coumarin-6 in the presence of cucurbit[7]uril","year":2015,"lang":"en","type":"article","venue":"MedChemComm","topic":"Supramolecular Chemistry and Complexes","field":"Chemistry","cited_by":59,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Natural Sciences and Engineering Research Council of Canada; Universidade de Macau","keywords":"Coumarin; In vivo; In vitro; Zebrafish; Chemistry; Biochemistry; Biology; Genetics; Gene; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001205014,0.0002866376,0.0001381749,0.0001050996,0.00008875211,0.0001021244,0.0001285222,0.0002032046,0.001056563],"category_scores_gemma":[0.00008930657,0.00009111795,0.0001029623,0.00009516312,0.0001533277,0.0001447519,0.00007837471,0.0002622718,0.0001817989],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002411682,"about_ca_system_score_gemma":0.0001468226,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002327204,"about_ca_topic_score_gemma":0.002974729,"domain_scores_codex":[0.9999402,0.00001472196,0.000003181972,0.00001204624,0.00001019012,0.0000196678],"domain_scores_gemma":[0.9999477,0.00001196807,0.00001630131,0.000005284034,0.000007864085,0.00001085281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001519204,0.00001294872,0.00003382304,0.00003612078,0.000002533084,0.00002358357,0.000009351284,0.00008465655,0.9990528,0.00004870572,0.00003168849,0.0005117338],"study_design_scores_gemma":[0.000004717635,0.0001916018,0.0004073394,0.000001579977,0.000006004911,0.00002223946,0.000005818649,0.0003459944,0.9985506,0.000003656557,0.0004584303,0.000002007604],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954177,0.0009813599,0.001360674,0.00007793052,0.00001941882,0.00001942949,0.000202291,0.00007904135,0.001842158],"genre_scores_gemma":[0.9949723,0.000622123,0.001369237,0.00002466715,0.0000047833,0.00001432789,0.0001858842,0.00001198239,0.002794636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002327204,"threshold_uncertainty_score":0.004627287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02016113538519724,"score_gpt":0.2437613306560596,"score_spread":0.2236001952708624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}