{"id":"W2106479312","doi":"10.1523/jneurosci.20-16-06218.2000","title":"Modulation of Absence Seizures by the GABA<sub>A</sub> Receptor: A Critical Role for Metabotropic Glutamate Receptor 4 (mGluR4)","year":2000,"lang":"en","type":"article","venue":"Journal of Neuroscience","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"Holland Bloorview Kids Rehabilitation Hospital; Hospital for Sick Children; University of Toronto","funders":"Medical Research Council; Medical Research Council Canada; Children's Hospital Foundation","keywords":"Pharmacology; Baclofen; Bicuculline; GABA receptor antagonist; GABAergic; Metabotropic glutamate receptor; Glutamate receptor; Agonist; gamma-Aminobutyric acid; Chemistry; Epilepsy; GABA receptor; Antagonist; GABAA receptor; Medicine; Receptor; Biology; Neuroscience; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009747183,0.0002598478,0.0004053767,0.0002227528,0.0006559734,0.0001787013,0.001672625,0.00008005291,0.00008394857],"category_scores_gemma":[0.003718263,0.0001816708,0.0002533148,0.001216462,0.001728243,0.001121668,0.0001177059,0.0006208585,0.00003373217],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003928006,"about_ca_system_score_gemma":0.000222485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001781178,"about_ca_topic_score_gemma":3.961068e-7,"domain_scores_codex":[0.9957157,0.0006530895,0.0008405637,0.0006535174,0.00137669,0.000760446],"domain_scores_gemma":[0.9970766,0.001522709,0.0004495942,0.0003879696,0.0002688042,0.0002943157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003126356,0.0002444963,0.00007674135,0.00001772563,0.000001359693,0.00002596605,0.00008226168,0.0003869205,0.9908653,0.0001727363,0.002762154,0.005051709],"study_design_scores_gemma":[0.0005180418,0.001200898,0.001315445,0.00002610974,0.00001856238,0.0003957341,0.00001831972,0.005734553,0.9749632,0.0003493645,0.01529192,0.0001678542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9941871,0.0001255849,0.0003599151,0.003169739,0.00153392,0.0004189901,0.00009511694,0.0000271279,0.00008249857],"genre_scores_gemma":[0.9957395,0.001158403,0.00009574351,0.002513424,0.0001859027,0.00002190961,1.926236e-7,0.00002887973,0.0002560835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01590209,"threshold_uncertainty_score":0.7408319,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0398560045482186,"score_gpt":0.3389418406662339,"score_spread":0.2990858361180153,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}