{"id":"W2106497825","doi":"10.1016/j.blre.2013.02.003","title":"Current status and future prospects for the prophylactic management of hemophilia patients with inhibitor antibodies","year":2013,"lang":"en","type":"review","venue":"Blood Reviews","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"St. Michael's Hospital","funders":"","keywords":"Medicine; Hemostasis; Recombinant factor VIIa; Factor IX; Prophylactic treatment; Adverse effect; PROTHROMBIN COMPLEX; Intensive care medicine; Surgery; Coagulation; Antibody; Internal medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002876105,0.0005274594,0.002211927,0.000121066,0.0001217366,0.00003580841,0.0001525592,0.0001235843,0.00003510212],"category_scores_gemma":[0.00003125482,0.0002003144,0.0004103508,0.0003207982,0.0001518775,0.00005598881,0.0001190351,0.0003341319,0.00002731189],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005075286,"about_ca_system_score_gemma":0.0001417316,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001921685,"about_ca_topic_score_gemma":5.805077e-7,"domain_scores_codex":[0.9977722,0.0001054248,0.0007466673,0.0005010072,0.0004421794,0.0004325729],"domain_scores_gemma":[0.9983626,0.00008738315,0.0005186124,0.0006657353,0.0001980821,0.0001675989],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002288127,0.000508591,0.0005793187,0.2332919,0.0006091365,0.000004121537,0.00003028332,9.378451e-10,7.371575e-8,0.00005707648,0.0004323828,0.7644642],"study_design_scores_gemma":[0.001632086,0.000786731,0.0005402714,0.03613085,0.008952396,0.000007987283,0.0000133336,1.652785e-7,0.000002389393,0.00000555477,0.9517245,0.0002037286],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002921531,0.9740953,8.420838e-7,0.0000903966,0.0002195917,0.02510234,0.00004756271,0.00001469882,0.0001370822],"genre_scores_gemma":[0.0000151242,0.9951244,0.0008601908,0.000007354095,0.0005157258,0.002567588,0.0001760749,0.00006090654,0.0006726658],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9512921,"threshold_uncertainty_score":0.8168585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04857161361746926,"score_gpt":0.3507530501066154,"score_spread":0.3021814364891462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}