{"id":"W2106647459","doi":"10.1161/hypertensionaha.113.03021","title":"Caspase Recruitment Domain 6 Protects Against Cardiac Hypertrophy in Response to Pressure Overload","year":2014,"lang":"en","type":"article","venue":"Hypertension","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Collaborative Innovation Center for Cardiovascular Disease Translational Medicine; University of Toronto","keywords":"Pressure overload; Cardiac hypertrophy; Internal medicine; Cardiology; Muscle hypertrophy; Medicine; Apoptosis; Endocrinology; Biology; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004517398,0.0001707214,0.0002311537,0.00009324824,0.00006779483,0.00001346937,0.00009989539,0.0002184636,0.00001267178],"category_scores_gemma":[0.0004085518,0.0001501407,0.00008604187,0.0001201188,0.00002594237,0.000002882576,0.0001006504,0.0001135966,0.00008643531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001628392,"about_ca_system_score_gemma":0.00004114701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002931215,"about_ca_topic_score_gemma":0.00002547688,"domain_scores_codex":[0.998382,0.0005497139,0.0001891516,0.0004774169,0.0001330345,0.000268631],"domain_scores_gemma":[0.9992177,0.00002998896,0.00004088652,0.0004994406,0.00007075493,0.0001411744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002183164,0.00005790501,0.0001716911,0.000008560307,0.00001299598,0.00002343502,0.00005717991,0.0001786484,0.985657,0.00001998627,0.008711422,0.002917973],"study_design_scores_gemma":[0.001097137,0.0009449684,0.002626334,0.00003164383,0.00001073024,0.0000299247,0.00004099941,0.00007587043,0.1520921,0.00002701762,0.8427773,0.0002460117],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956542,0.0003367451,0.000696286,0.0006399337,0.0007465434,0.0009536946,0.00001425344,0.00002115119,0.0009372566],"genre_scores_gemma":[0.9917981,0.00005537498,0.0023887,0.00362653,0.0003947736,0.0002327093,0.00006294117,0.00003103012,0.001409852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8340659,"threshold_uncertainty_score":0.6122558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02236249418359573,"score_gpt":0.2440581892673042,"score_spread":0.2216956950837084,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}