{"id":"W2106647992","doi":"10.1101/gad.200113.112","title":"Genome-wide identification of enhancers in skeletal muscle: the role of MyoD1","year":2012,"lang":"en","type":"article","venue":"Genes & Development","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":180,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"National Institute of General Medical Sciences; National Cancer Institute; National Institute on Aging; National Institutes of Health; York University","keywords":"Myogenesis; Biology; Enhancer; Chromatin; Transcription factor; Histone; Enhancer RNAs; Genetics; Cell biology; Mef2; Myocyte; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003058982,0.0001369048,0.0002429675,0.0003770101,0.0001379795,0.000258018,0.0001700114,0.0001628471,0.0006632936],"category_scores_gemma":[0.0001995536,0.0001457312,0.0001543884,0.0003091352,0.0001362589,0.00008571353,0.0003021551,0.0002923002,0.0001581348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001877654,"about_ca_system_score_gemma":0.0001482719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006316292,"about_ca_topic_score_gemma":0.002449275,"domain_scores_codex":[0.999896,0.00001130994,0.000005910691,0.00004919724,0.0000270285,0.00001037922],"domain_scores_gemma":[0.9998958,0.00003126069,0.00002868727,0.00001347756,0.00001079255,0.00001991056],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002603173,0.00002088839,0.02834867,0.0001583144,0.00006085738,0.0001090096,0.00006000383,0.00029885,0.9589976,0.000222178,0.0001643339,0.01129895],"study_design_scores_gemma":[0.00004820696,0.000105177,0.8081329,0.00002385967,0.0001647651,0.001092145,0.00006503706,0.003096887,0.1772047,0.0003034256,0.009745414,0.00001737638],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867396,0.004404319,0.005318135,0.0001099904,0.000008274286,0.00002128796,0.0020985,0.0001049193,0.001194951],"genre_scores_gemma":[0.9881918,0.001031018,0.005891264,0.0001026099,0.000009541754,0.0000255761,0.003592096,0.00002746662,0.001128711],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006632936,"threshold_uncertainty_score":0.002218902,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00702523139222026,"score_gpt":0.2460209468074711,"score_spread":0.2389957154152508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}