{"id":"W2106667548","doi":"10.1128/aac.45.8.2238-2244.2001","title":"Overexpression and Characterization of the Chromosomal Aminoglycoside 2′- <i>N</i> -Acetyltransferase of <i>Providencia stuartii</i>","year":2001,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Acetyltransferase; Enzyme; Chloramphenicol acetyltransferase; Providencia; Biochemistry; Enzyme kinetics; Affinity chromatography; Aminoglycoside; Molecular biology; Biology; Escherichia coli; Chemistry; Active site; Enterobacteriaceae; Antibiotics; Reporter gene; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004237767,0.0001137922,0.0001440304,0.00001702426,0.00005169985,0.00001019588,0.0001093177,0.000149319,0.00001275416],"category_scores_gemma":[0.000003433134,0.00008318944,0.00004662648,0.00006295925,0.0001697019,0.000004768543,0.00007135632,0.00004349516,1.556146e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001898544,"about_ca_system_score_gemma":0.00001773064,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002086578,"about_ca_topic_score_gemma":0.000006887748,"domain_scores_codex":[0.999414,0.0000230698,0.0001912974,0.0001961438,0.00005665039,0.00011886],"domain_scores_gemma":[0.9996437,0.000002381,0.0001056886,0.0001855864,0.00003637084,0.00002625091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001384704,0.00006921132,0.02153364,0.00002662015,0.00002272978,3.113763e-7,0.00004893505,2.588725e-7,0.9740196,0.000009202698,0.000254058,0.003876938],"study_design_scores_gemma":[0.0006732867,0.0001623463,0.07995696,0.00004649729,0.00001058891,0.00001747803,0.000007581931,0.000005982345,0.9044713,0.000007542289,0.01455329,0.00008712071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988832,0.00003400412,0.00005850864,0.0007024463,0.00006611529,0.0001740327,0.00004823722,0.000003870355,0.00002961131],"genre_scores_gemma":[0.9948218,0.003650344,0.00007474458,0.001268319,0.00006225195,0.000002009297,0.00003121378,0.00001272337,0.00007661698],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06954829,"threshold_uncertainty_score":0.3392367,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00561032465671901,"score_gpt":0.2054012199798023,"score_spread":0.1997908953230833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}