{"id":"W2106667548","doi":"10.1128/aac.45.8.2238-2244.2001","title":"Overexpression and Characterization of the Chromosomal Aminoglycoside 2′- <i>N</i> -Acetyltransferase of <i>Providencia stuartii</i>","year":2001,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Acetyltransferase; Enzyme; Chloramphenicol acetyltransferase; Providencia; Biochemistry; Enzyme kinetics; Affinity chromatography; Aminoglycoside; Molecular biology; Biology; Escherichia coli; Chemistry; Active site; Enterobacteriaceae; Antibiotics; Reporter gene; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001969321,0.0005797896,0.0004702373,0.0002655539,0.000182706,0.0004203714,0.0004784722,0.0003802565,0.0004868407],"category_scores_gemma":[0.000323063,0.0002193935,0.0004919494,0.0005168114,0.0002345639,0.0001899967,0.0003172767,0.000574313,0.0007204902],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006515458,"about_ca_system_score_gemma":0.0003909015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004935364,"about_ca_topic_score_gemma":0.003597518,"domain_scores_codex":[0.9997712,0.00002935419,0.00002910498,0.00004723268,0.00007929533,0.00004389101],"domain_scores_gemma":[0.9997035,0.0000445518,0.00008464667,0.00005155384,0.0000545333,0.00006116311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000023615,0.00001138539,0.0000836346,0.00002288727,0.000002341859,0.00003731645,0.00001531154,0.00003949797,0.999267,0.00004509262,0.00001685309,0.0004350765],"study_design_scores_gemma":[0.000007605427,0.00008004533,0.004379454,0.000006589887,0.00001298323,0.000347783,0.00003479756,0.0005035854,0.9907593,0.00002158123,0.00383623,0.00001005267],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797219,0.001150907,0.01408669,0.0001619799,0.00004562164,0.00009630986,0.002916982,0.0003024105,0.001517224],"genre_scores_gemma":[0.9667792,0.001287403,0.01665477,0.00007048098,0.00001928378,0.00009966103,0.008913485,0.0001933651,0.005982354],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004935364,"threshold_uncertainty_score":0.009813249,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00561032465671901,"score_gpt":0.2054012199798023,"score_spread":0.1997908953230833,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}