{"id":"W2106682709","doi":"10.1016/j.febslet.2004.07.016","title":"Prp8 intein in fungal pathogens: target for potential antifungal drugs","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Intein; Cryptococcus neoformans; Aspergillus fumigatus; Biology; Microbiology; Aspergillus nidulans; Protein splicing; Computational biology; RNA splicing; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002408614,0.000166513,0.0001508493,0.00005947517,0.00006190383,0.00002833667,0.0001860176,0.0001382132,0.00002409585],"category_scores_gemma":[0.00004273854,0.0001662122,0.0001398468,0.00006102663,0.00003959348,0.000005596849,0.00005555484,0.00007173689,0.00001331362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002494557,"about_ca_system_score_gemma":0.00004355962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001939181,"about_ca_topic_score_gemma":0.000007919959,"domain_scores_codex":[0.9989189,0.00004949127,0.0002035043,0.0003676947,0.0001166088,0.0003438139],"domain_scores_gemma":[0.9996054,0.000007510049,0.00006082184,0.000242917,0.00002554871,0.00005782618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001561762,0.00004398129,0.0001909932,0.00001813596,0.00002236199,0.00002126863,0.00005503524,0.0004435104,0.9961145,0.0001136964,0.001274237,0.001546102],"study_design_scores_gemma":[0.001084571,0.0002156074,0.0002805107,0.00002748174,0.0000105459,0.00001810929,0.0000552427,0.00001413561,0.9867617,0.0004254187,0.01086,0.0002466313],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9391333,0.0002810243,0.05731351,0.00230678,0.0003587315,0.0004262553,0.00005172403,0.00001627283,0.0001124157],"genre_scores_gemma":[0.9852218,0.00002014365,0.01170904,0.002258071,0.000418501,0.0001025637,0.0001050303,0.00003401118,0.0001308661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04608849,"threshold_uncertainty_score":0.6777939,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006256645828978993,"score_gpt":0.216248343487239,"score_spread":0.20999169765826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}