{"id":"W2106682709","doi":"10.1016/j.febslet.2004.07.016","title":"Prp8 intein in fungal pathogens: target for potential antifungal drugs","year":2004,"lang":"en","type":"article","venue":"FEBS Letters","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"","keywords":"Intein; Cryptococcus neoformans; Aspergillus fumigatus; Biology; Microbiology; Aspergillus nidulans; Protein splicing; Computational biology; RNA splicing; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00012753,0.0002313692,0.0002262281,0.0002347671,0.0001390754,0.0002448164,0.0001334359,0.0002984221,0.0006907949],"category_scores_gemma":[0.0001147319,0.00009997949,0.0001226513,0.00013758,0.0002066795,0.000189391,0.0001412068,0.0003662287,0.0002758369],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001643234,"about_ca_system_score_gemma":0.0001024254,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001019035,"about_ca_topic_score_gemma":0.0001827591,"domain_scores_codex":[0.9999501,0.00001286505,0.000004100271,0.000008234589,0.00001551142,0.00000928117],"domain_scores_gemma":[0.9999447,0.00001527154,0.000009358409,0.000006740867,0.000009119974,0.00001475154],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000153393,0.00002540911,0.0008305603,0.00006067061,0.000004072539,0.0003292195,0.00001111764,0.0001743664,0.9883342,0.0004123427,0.00009014688,0.009574449],"study_design_scores_gemma":[0.00001672961,0.0002849282,0.007168241,0.00001303579,0.00002476717,0.002213449,0.00002553281,0.001357355,0.9822352,0.0003474255,0.006307784,0.000005374204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9743845,0.01324515,0.007218867,0.000524054,0.00003741441,0.00003612763,0.0001754282,0.0001253012,0.004253199],"genre_scores_gemma":[0.988801,0.003736763,0.005028293,0.0001235831,0.00001560686,0.00001106059,0.0002700215,0.000008196378,0.002005526],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006907949,"threshold_uncertainty_score":0.002310932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006256645828978993,"score_gpt":0.216248343487239,"score_spread":0.20999169765826,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}