{"id":"W2106697715","doi":"10.1128/jvi.00858-09","title":"Human Endogenous Retroviral Long Terminal Repeat Sequences as Cell Type-Specific Promoters in Retroviral Vectors","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Chromosomal and Genetic Variations","field":"Agricultural and Biological Sciences","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Terry Fox Research Institute","funders":"","keywords":"Long terminal repeat; Biology; Promoter; Endogenous retrovirus; Retrovirus; Gene; Reporter gene; Murine leukemia virus; Genetics; Transfection; Expression vector; Transcription (linguistics); Virology; Molecular biology; Genome; Gene expression; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001513459,0.0007753375,0.0007438791,0.0008745177,0.0004199955,0.001081962,0.001542243,0.0008317124,0.004006566],"category_scores_gemma":[0.0006610013,0.0008557755,0.0005581798,0.001003382,0.0005716139,0.000649014,0.0006481941,0.002350892,0.00591508],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006745662,"about_ca_system_score_gemma":0.0006072255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003701056,"about_ca_topic_score_gemma":0.0007629832,"domain_scores_codex":[0.9984025,0.0005021147,0.0001840482,0.0002338317,0.0004678304,0.0002096578],"domain_scores_gemma":[0.9996488,0.00007920718,0.00005324579,0.0001117582,0.00005247346,0.00005448784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005364512,0.0002361093,0.0002930204,0.0003853232,0.00002883632,0.0001916702,0.0001899553,0.0006145228,0.9705132,0.005474994,0.002030215,0.01950562],"study_design_scores_gemma":[0.0001733992,0.0004270758,0.0006926534,0.00007229235,0.00006049361,0.0006218831,0.00005216591,0.00243564,0.8806001,0.0008553454,0.113973,0.00003589173],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3352224,0.01199524,0.5970777,0.0007894142,0.001947087,0.006285663,0.01997789,0.005919393,0.02078529],"genre_scores_gemma":[0.4741444,0.008428513,0.4161139,0.0004917213,0.0002590943,0.003784356,0.04308951,0.001530747,0.05215783],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004006566,"threshold_uncertainty_score":0.0134033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02500093612021374,"score_gpt":0.2383883079161092,"score_spread":0.2133873717958954,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}