{"id":"W2106773063","doi":"10.1093/jnci/93.19.1473","title":"In Vitro Evidence for Homologous Recombinational Repair in Resistance to Melphalan","year":2001,"lang":"en","type":"article","venue":"JNCI Journal of the National Cancer Institute","topic":"Melanoma and MAPK Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Melphalan; XRCC3; RAD51; Ku80; DNA repair; Ku70; Homologous recombination; Nitrogen mustard; DNA damage; Biology; Non-homologous end joining; RAD52; ERCC1; DNA; Molecular biology; Cancer research; Genetics; Nucleotide excision repair; DNA-binding protein; Gene; Transcription factor; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006874602,0.0003901422,0.0002159494,0.0003427078,0.0001125286,0.0003630631,0.000366132,0.0003631889,0.004410726],"category_scores_gemma":[0.001140899,0.0001503488,0.0003202839,0.0002272465,0.0002241285,0.0001834862,0.0002238957,0.0005792895,0.001541842],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003450947,"about_ca_system_score_gemma":0.0001853029,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004809991,"about_ca_topic_score_gemma":0.0003964518,"domain_scores_codex":[0.9994304,0.000163623,0.00008141334,0.00007339325,0.0001909698,0.00006023551],"domain_scores_gemma":[0.9979423,0.0008766548,0.0004898537,0.0003067295,0.0002767312,0.0001077503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002318201,0.00009494671,0.002779864,0.0001379969,0.00004290093,0.0001487027,0.00003201136,0.000138219,0.99415,0.0002542304,0.0001059203,0.001883427],"study_design_scores_gemma":[0.00002292108,0.0004644387,0.01739538,0.00001745713,0.00005819152,0.001468567,0.00004062039,0.001154025,0.9758985,0.000153887,0.003319319,0.000006732349],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9637837,0.01123646,0.01578016,0.0003478089,0.00009413488,0.00009200821,0.001243725,0.0002856307,0.007136442],"genre_scores_gemma":[0.9924838,0.001068262,0.003239692,0.00005877821,0.00001793323,0.00003871225,0.001431222,0.00002137225,0.001640186],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004410726,"threshold_uncertainty_score":0.01475531,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07110099166967875,"score_gpt":0.359029660498361,"score_spread":0.2879286688286822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}