{"id":"W2106807427","doi":"10.1242/dmm.007419","title":"A <i>Drosophila</i> model for the Zellweger spectrum of peroxisome biogenesis disorders","year":2011,"lang":"en","type":"article","venue":"Disease Models & Mechanisms","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research; Howard Hughes Medical Institute","keywords":"Zellweger syndrome; Peroxisome; Biology; Peroxisomal disorder; Biogenesis; Cell biology; Lipid metabolism; Mutation; Genetics; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001715529,0.0003147826,0.0002334631,0.00006730447,0.0001676642,0.00001554381,0.0005035247,0.0001594348,0.00003082604],"category_scores_gemma":[0.00002972938,0.0002442049,0.0003629875,0.0001241341,0.0001208109,0.00001673359,0.000159132,0.0000753724,0.000004564668],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001734968,"about_ca_system_score_gemma":0.0001567936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002622051,"about_ca_topic_score_gemma":0.00001555591,"domain_scores_codex":[0.9984299,0.00004254474,0.0002990145,0.0005521926,0.0002379964,0.0004383631],"domain_scores_gemma":[0.9988068,0.00001492504,0.0001373988,0.0007162698,0.00008962688,0.0002350007],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001223462,0.0005283533,0.0001263272,0.00007856148,0.0003005857,9.466436e-7,0.0003836448,0.01401782,0.9587642,0.02354142,0.0003374979,0.0006971654],"study_design_scores_gemma":[0.0006296847,0.0001757386,0.00002614759,0.00001149701,0.0001479123,9.680521e-7,0.00006651688,0.1852714,0.6957356,0.117471,0.0001184001,0.0003452098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.3420673,0.001500353,0.6542003,0.0003200092,0.0002141718,0.0009173398,0.0005678828,0.00004274802,0.0001698601],"genre_scores_gemma":[0.9947617,0.0005582725,0.003407247,0.0003829491,0.00008739426,0.0003915896,0.0001200671,0.00008849795,0.0002022906],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6526943,"threshold_uncertainty_score":0.9958389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02776042658197238,"score_gpt":0.2256541150251922,"score_spread":0.1978936884432198,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}