{"id":"W2106910870","doi":"10.1128/jvi.00142-09","title":"Cell Fusion-Induced Activation of Interferon-Stimulated Genes Is Not Required for Restriction of a Herpes Simplex Virus VP16/ICP0 Mutant in Heterokarya Formed between Permissive and Restrictive Cells","year":2009,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Herpesvirus Infections and Treatments","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; Fondation pour la Recherche Médicale","keywords":"Biology; Cell fusion; Herpes simplex virus; Vero cell; Mutant; Sendai virus; Virology; Interferon; Phenotype; Virus; Molecular biology; Lipid bilayer fusion; Fusion gene; Permissive; Gene; Cell culture; Permissiveness; Viral replication; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001992695,0.0002055575,0.0003443872,0.0001981993,0.0002187681,0.0003704652,0.000226851,0.0002227767,0.001820295],"category_scores_gemma":[0.000211255,0.0002012281,0.0002995924,0.0001275484,0.0003305864,0.0002288512,0.0003061885,0.0005900712,0.0005240988],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003048774,"about_ca_system_score_gemma":0.0003212374,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004947874,"about_ca_topic_score_gemma":0.0006405636,"domain_scores_codex":[0.9997248,0.00003688392,0.00002789447,0.00005515373,0.00009528619,0.00005995811],"domain_scores_gemma":[0.9997076,0.00007713752,0.00005083854,0.0000636712,0.00002098076,0.00007966001],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003962551,0.00001136606,0.00010802,0.000005792667,0.000001745449,0.0000285245,0.00001578646,0.000008906132,0.9994722,0.00008522619,0.000008902583,0.0002138057],"study_design_scores_gemma":[0.00001028781,0.0001732554,0.004976028,0.000003492467,0.000006519836,0.0003577712,0.00004678256,0.0004492107,0.9928382,0.00006358037,0.001071177,0.000003653745],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968339,0.0003747483,0.001587639,0.00002670578,0.00001728122,0.00001740769,0.0001374716,0.00004033634,0.0009647331],"genre_scores_gemma":[0.9965582,0.0001309069,0.001180662,0.00001578716,0.000005501688,0.00002413741,0.0003710464,0.00003115938,0.001682546],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001820295,"threshold_uncertainty_score":0.006089509,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04045146766279658,"score_gpt":0.3267619066334865,"score_spread":0.2863104389706899,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}