{"id":"W2106947070","doi":"10.2353/ajpath.2008.080081","title":"Matrix Metalloproteinase-8 Facilitates Neutrophil Migration through the Corneal Stromal Matrix by Collagen Degradation and Production of the Chemotactic Peptide Pro-Gly-Pro","year":2008,"lang":"en","type":"article","venue":"American Journal Of Pathology","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":169,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Center for Research Resources; National Center for Complementary and Integrative Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; National Institute of Diabetes and Digestive and Kidney Diseases; National Eye Institute; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; Canada Research Chairs; University of Alabama at Birmingham; National Cancer Institute; Case Western Reserve University; Ohio Lions Eye Research Foundation; Cystic Fibrosis Foundation; Research to Prevent Blindness; Prevent Blindness Ohio","keywords":"Chemotaxis; Stromal cell; Matrix metalloproteinase; Matrix (chemical analysis); Cell biology; Peptide; Matrix Metalloproteinase 3; Chemistry; Degradation (telecommunications); Immunology; Biochemistry; Biology; Cancer research; Computer science; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002933153,0.000140608,0.0002381689,0.00002877988,0.0001548848,0.000008830471,0.0001774481,0.00006477498,0.000003876034],"category_scores_gemma":[0.0001922498,0.00008637785,0.0001110565,0.0001463269,0.0004992881,0.000023167,0.00005796503,0.0001278929,8.575207e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001818832,"about_ca_system_score_gemma":0.0001125801,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005294149,"about_ca_topic_score_gemma":0.000009001502,"domain_scores_codex":[0.9987705,0.0003078158,0.0003753454,0.0002011662,0.0001815211,0.0001635971],"domain_scores_gemma":[0.9987891,0.00001753134,0.0007132919,0.0002430104,0.0001993215,0.00003778817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000214062,0.00005496142,0.0006508914,0.00001065931,0.000047503,0.00001159299,0.0003024095,0.00002727259,0.9970915,0.00003487407,0.0008518301,0.0007024466],"study_design_scores_gemma":[0.0003944934,0.002225374,0.001594616,0.00001357151,0.00008085529,0.002487588,0.0008142828,0.00001831767,0.9901153,0.0002680657,0.00187424,0.0001132303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955801,0.001185951,0.001020598,0.001671703,0.0001548098,0.000349266,0.00001752477,0.000003523058,0.00001651751],"genre_scores_gemma":[0.996511,0.000478267,0.0023953,0.00008879516,0.0001707363,0.00001690823,0.00001441587,0.0000130756,0.0003114828],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006976132,"threshold_uncertainty_score":0.3522387,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01083405074824194,"score_gpt":0.2439098611827118,"score_spread":0.2330758104344698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}