{"id":"W2106958989","doi":"10.1017/s0007114511003631","title":"Comparative effects of retinoic acid, vitamin D and resveratrol alone and in combination with adenosine analogues on methylation and expression of phosphatase and tensin homologue tumour suppressor gene in breast cancer cells","year":2011,"lang":"en","type":"article","venue":"British Journal Of Nutrition","topic":"RNA modifications and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":114,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Uniwersytet Łódzki","keywords":"Tensin; PTEN; Cancer research; DNA methylation; Epigenetics; Biology; Carcinogenesis; Retinoic acid; Methylation; Resveratrol; Tumor suppressor gene; Molecular biology; Gene expression; Chemistry; Biochemistry; PI3K/AKT/mTOR pathway; Gene; Signal transduction","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001711856,0.0002932406,0.0005201508,0.0003157438,0.0001244602,0.0002302567,0.0001978351,0.0003131465,0.0007709453],"category_scores_gemma":[0.000172521,0.0001766757,0.0004593567,0.0002745725,0.0001730626,0.0002301477,0.0001356626,0.0004068381,0.0002265568],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001592069,"about_ca_system_score_gemma":0.0002012901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001281799,"about_ca_topic_score_gemma":0.001882879,"domain_scores_codex":[0.9997507,0.00007795411,0.00003639228,0.00004260678,0.00004929885,0.00004302839],"domain_scores_gemma":[0.9998319,0.00005581378,0.0000263094,0.00002378707,0.00002850996,0.00003368389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009754268,0.0001080932,0.0002670632,0.0001032806,0.0000324729,0.00005408427,0.00005649753,0.0001098932,0.9960438,0.00004730731,0.00006192614,0.002140128],"study_design_scores_gemma":[0.00005694127,0.003054037,0.005854073,0.000009468822,0.0001160837,0.0001621481,0.0001229337,0.0005179291,0.9872276,0.00004234382,0.002821764,0.00001475257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9908972,0.006322013,0.0005210426,0.000101003,0.00006177784,0.00002938969,0.0003457883,0.00002947583,0.001692422],"genre_scores_gemma":[0.9930277,0.003185869,0.001070449,0.00006934407,0.00002122449,0.00004206748,0.0004902911,0.000009109313,0.002083897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001281799,"threshold_uncertainty_score":0.002579093,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009707395154878482,"score_gpt":0.2286975698607484,"score_spread":0.2189901747058699,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}